Doxorubicin

ABL proto-oncogene 1, non-receptor tyrosine kinase ; Homo sapiens







17 Article(s)
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1 30057314 Direct and rapid identification of T315I-Mutated BCR-ABL expressing leukemic cells using infrared microspectroscopy. 2018 Sep 10 1
2 27144331 Liposomal bortezomib is active against chronic myeloid leukemia by disrupting the Sp1-BCR/ABL axis. 2016 Jun 14 1
3 26217035 c-Abl-mediated tyrosine phosphorylation of JunB is required for Adriamycin-induced expression of p21. 2015 Oct 1 6
4 26218127 Coupled delivery of imatinib mesylate and doxorubicin with nanoscaled polymeric vectors for a sustained downregulation of BCR-ABL in chronic myeloid leukemia. 2015 Feb 2
5 26618175 Doxorubicin Differentially Induces Apoptosis, Expression of Mitochondrial Apoptosis-Related Genes, and Mitochondrial Potential in BCR-ABL1-Expressing Cells Sensitive and Resistant to Imatinib. 2015 1
6 24177958 c-ABL tyrosine kinase modulates p53-dependent p21 induction and ensuing cell fate decision in response to DNA damage. 2014 Feb 2
7 23383209 Imatinib reverses doxorubicin resistance by affecting activation of STAT3-dependent NF-κB and HSP27/p38/AKT pathways and by inhibiting ABCB1. 2013 1
8 23441067 Alantolactone inhibits growth of K562/adriamycin cells by downregulating Bcr/Abl and P-glycoprotein expression. 2013 May 1
9 23892407 Doxorubicin induces atypical NF-κB activation through c-Abl kinase activity in breast cancer cells. 2013 Oct 2
10 24041959 Formation of long and winding nuclear F-actin bundles by nuclear c-Abl tyrosine kinase. 2013 Dec 10 4
11 21356308 Activation of STAT5 confers imatinib resistance on leukemic cells through the transcription of TERT and MDR1. 2011 Jul 1
12 22001646 Nuclear c-Abl-mediated tyrosine phosphorylation induces chromatin structural changes through histone modifications that include H4K16 hypoacetylation. 2011 Dec 10 1
13 17957275 Combined effects of doxorubicin and STI571 on growth, differentiation and apoptosis of CML cell line K562. 2007 1
14 15846067 Kinase-addiction and bi-phasic sensitivity-resistance of Bcr-Abl- and Raf-1-expressing cells to imatinib and geldanamycin. 2005 Apr 2
15 12359059 Significance of nuclear glutathione S-transferase pi in resistance to anti-cancer drugs. 2002 Sep 1
16 11587211 The Hsp90 inhibitor geldanamycin selectively sensitizes Bcr-Abl-expressing leukemia cells to cytotoxic chemotherapy. 2001 Oct 4
17 10979973 CGP57148B (STI-571) induces differentiation and apoptosis and sensitizes Bcr-Abl-positive human leukemia cells to apoptosis due to antileukemic drugs. 2000 Sep 15 2