Proline

ABL proto-oncogene 1, non-receptor tyrosine kinase ; Homo sapiens







44 Article(s)
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1 35561654 Design, synthesis, and biological evaluation of trizole-based heteroaromatic derivatives as Bcr-Abl kinase inhibitors. 2022 Aug 5 1
2 33903307 H396P mutation in chronic myeloid leukaemia patient on nilotinib - A case report. 2021 Apr 1
3 31296381 Solution NMR structure and ligand identification of human Gas7 SH3 domain reveal a typical SH3 fold but a non-canonical ligand-binding mode. 2019 Sep 3 1
4 27161995 Parallel Chemical Protein Synthesis on a Surface Enables the Rapid Analysis of the Phosphoregulation of SH3 Domains. 2016 Jun 13 1
5 27332121 Binding Mechanism of the N-Terminal SH3 Domain of CrkII and Proline-Rich Motifs in cAbl. 2016 Jun 21 2
6 27806266 Kinetic Insights into the Binding between the nSH3 Domain of CrkII and Proline-Rich Motifs in cAbl. 2016 Nov 1 2
7 24480037 Serine and proline-rich ligands enriched via phage-display technology show preferential binding to BCR/ABL expressing cells. 2014 Mar 2
8 23325923 c-Abl tyrosine kinase plays a critical role in β2 integrin-dependent neutrophil migration by regulating Vav1 activity. 2013 Apr 1
9 22253690 Modeling of molecular interaction between apoptin, BCR-Abl and CrkL--an alternative approach to conventional rational drug design. 2012 1
10 22675626 Functional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics. 2012 1
11 21320496 Identification and functional analysis of a new phosphorylation site (Y398) in the SH3 domain of Abi-1. 2011 Mar 23 1
12 19906645 Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl. 2010 Jan 22 2
13 19442657 Evidence for a direct involvement of hMSH5 in promoting ionizing radiation induced apoptosis. 2009 Aug 15 1
14 19470755 Cdo binds Abl to promote p38alpha/beta mitogen-activated protein kinase activity and myogenic differentiation. 2009 Aug 2
15 15632178 Mitotic phosphorylation rescues Abl from F-actin-mediated inhibition. 2005 Mar 18 1
16 16285507 Homodimerization of the c-Abl protein tyrosine kinase. 2005 Sep 2
17 14757063 Thermodynamic dissection of the binding energetics of proline-rich peptides to the Abl-SH3 domain: implications for rational ligand design. 2004 Feb 13 1
18 15289338 Effect of mutational inactivation of tyrosine kinase activity on BCR/ABL-induced abnormalities in cell growth and adhesion in human hematopoietic progenitors. 2004 Aug 1 1
19 15313630 A miniprotein scaffold used to assemble the polyproline II binding epitope recognized by SH3 domains. 2004 Sep 3 1
20 12569093 Functional interaction between the c-Abl and Arg protein-tyrosine kinases in the oxidative stress response. 2003 Apr 11 1
21 12777393 Dok-R binds c-Abl and regulates Abl kinase activity and mediates cytoskeletal reorganization. 2003 Aug 8 1
22 12893824 Glutathione peroxidase 1 is regulated by the c-Abl and Arg tyrosine kinases. 2003 Oct 10 1
23 11840343 Regulation of p73 by c-Abl through the p38 MAP kinase pathway. 2002 Jan 31 1
24 12384576 Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide. 2002 Oct 29 1
25 11380621 Crk family adaptor proteins trans-activate c-Abl kinase. 2001 May 3
26 11387320 Deletion of the Src homology 3 domain and C-terminal proline-rich sequences in Bcr-Abl prevents Abl interactor 2 degradation and spontaneous cell migration and impairs leukemogenesis. 2001 Aug 3 2
27 11494134 Regulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptor. 2001 Jul 5 3
28 11753652 Mutational analysis of the regulatory function of the c-Abl Src homology 3 domain. 2001 Nov 22 1
29 10611245 A novel PF/PN motif inhibits nuclear localization and DNA binding activity of the ESX1 homeoprotein. 2000 Jan 1
30 10879451 Evaluation of the Lactate Pro blood lactate analyser. 2000 May 1
31 11080615 The substrate specificity of the catalytic domain of Abl plays an important role in directing phosphorylation of the adaptor protein Crk. 2000 Oct 2
32 10194128 CRKL binding to BCR-ABL and BCR-ABL transformation. 1999 Mar 2
33 9843217 ATM associates with and phosphorylates p53: mapping the region of interaction. 1998 Dec 1
34 8978305 Direct binding of CRKL to BCR-ABL is not required for BCR-ABL transformation. 1997 Jan 1 7
35 9060613 The murine AIDS virus Gag precursor protein binds to the SH3 domain of c-Abl. 1997 Apr 1
36 9299869 New insights in biology and current therapeutic options for patients with chronic myelogenous leukemia. 1997 Jul-Aug 1
37 9376661 Signal transduction pathways involved in BCR-ABL transformation. 1997 Jun 1
38 8702917 A potential SH3 domain-binding site in the Crk SH2 domain. 1996 Aug 30 1
39 7535279 enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties. 1995 Mar 1 1
40 7590236 Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity. 1995 Nov 1 1
41 7664083 High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides. 1994 Aug 1
42 7773778 Structure of the N-terminal SH3 domain of GRB2 complexed with a peptide from the guanine nucleotide releasing factor Sos. 1994 Dec 1
43 7988556 Identification of Src, Fyn, Lyn, PI3K and Abl SH3 domain ligands using phage display libraries. 1994 Dec 1 1
44 8402898 The GTPase dynamin binds to and is activated by a subset of SH3 domains. 1993 Oct 8 1