Guanine Nucleotides

succinate-CoA ligase GDP/ADP-forming subunit alpha ; Homo sapiens







46 Article(s)
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1 34769272 Heterotrimeric G Proteins in Plants: Canonical and Atypical Gα Subunits. 2021 Oct 31 1
2 32126208 Structures of Gα Proteins in Complex with Their Chaperone Reveal Quality Control Mechanisms. 2020 Mar 17 1
3 31624147 Large-scale conformational rearrangement of the α5-helix of Gα subunits in complex with the guanine nucleotide exchange factor Ric8A. 2019 Nov 22 2
4 30406994 A Residue outside the Binding Site Determines the Gα Binding Specificity of GoLoco Motifs. 2018 Nov 27 1
5 28001387 Structural Determinants of Constitutive Activation of Gα Proteins: Transducin as a Paradigm. 2017 Feb 14 1
6 27558716 Nanosecond Dynamics of Gαi1 Bound to Nucleotides or Ric-8A, a Gα Chaperone with GEF Activity. 2016 Aug 23 1
7 28008853 Ric-8A, a G protein chaperone with nucleotide exchange activity induces long-range secondary structure changes in Gα. 2016 Dec 23 1
8 25414258 Pivotal role of extended linker 2 in the activation of Gα by G protein-coupled receptor. 2015 Jan 2 1
9 25480567 Activator of G protein signaling 3 forms a complex with resistance to inhibitors of cholinesterase-8A without promoting nucleotide exchange on Gα(i3). 2015 Mar 2
10 24141076 Microbial fluorescence sensing for human neurotensin receptor type 1 using Gα-engineered yeast cells. 2014 Feb 1 1
11 24302560 Activators of G protein signaling exhibit broad functionality and define a distinct core signaling triad. 2014 Mar 1
12 24596087 A transient interaction between the phosphate binding loop and switch I contributes to the allosteric network between receptor and nucleotide in Gαi1. 2014 Apr 18 1
13 23200849 Gα(h)/transglutaminase-2 activity is required for maximal activation of adenylylcyclase 8 in human and rat glioma cells. 2013 Mar 1
14 23212907 Regulation of the G-protein regulatory-Gαi signaling complex by nonreceptor guanine nucleotide exchange factors. 2013 Feb 1 2
15 23576747 Dictyostelium Ric8 is a nonreceptor guanine exchange factor for heterotrimeric G proteins and is important for development and chemotaxis. 2013 Apr 16 1
16 22448927 A constitutively active Gα subunit provides insights into the mechanism of G protein activation. 2012 Apr 17 1
17 22952234 Crystal structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Gαi. 2012 Oct 26 1
18 21285355 A dominant-negative Galpha mutant that traps a stable rhodopsin-Galpha-GTP-betagamma complex. 2011 Apr 8 1
19 21607862 [³⁵S]GTPγS binding as an index of total G-protein and Gα-subtype-specific activation by GPCRs. 2011 2
20 21853086 The nucleotide exchange factor Ric-8A is a chaperone for the conformationally dynamic nucleotide-free state of Gαi1. 2011 1
21 20404072 Heterotrimeric G protein signaling outside the realm of seven transmembrane domain receptors. 2010 Jul 1
22 18302932 Neuroprotective function of human neuroglobin is correlated with its guanine nucleotide dissociation inhibitor activity. 2008 May 2 1
23 18541531 Ric-8A catalyzes guanine nucleotide exchange on G alphai1 bound to the GPR/GoLoco exchange inhibitor AGS3. 2008 Aug 22 1
24 19513240 A sweet cycle for Arabidopsis G-proteins: Recent discoveries and controversies in plant G-protein signal transduction. 2008 Dec 3
25 16949794 Differential G-alpha interaction capacities of the GoLoco motifs in Rap GTPase activating proteins. 2007 Feb 1
26 17463080 Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins. 2007 May 8 1
27 16687250 Mammalian RGS proteins: multifunctional regulators of cellular signalling. 2006 Jun 1
28 15723537 Identification of residues in human neuroglobin crucial for Guanine nucleotide dissociation inhibitor activity. 2005 Mar 1 1
29 15865441 The role of G beta gamma and domain interfaces in the activation of G protein-coupled receptor kinase 2. 2005 May 10 2
30 16243026 New roles for Galpha and RGS proteins: communication continues despite pulling sisters apart. 2005 Oct 25 1
31 14656218 Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif. 2004 Mar 15 1
32 15120622 Human neuroglobin interacts with flotillin-1, a lipid raft microdomain-associated protein. 2004 May 28 1
33 15250494 Measurement of agonist-stimulated [35S]GTPgammaS binding to assess total G-protein and Galpha-subtype-specific activation by G-protein-coupled receptors. 2004 2
34 15368366 Mutation of the highly conserved Arg165 and Glu168 residues of human Gsalpha disrupts the alphaD-alphaE loop and enhances basal GDP/GTP exchange rate. 2004 Oct 1 1
35 15613689 Plant G proteins, phytohormones, and plasticity: three questions and a speculation. 2004 Dec 21 1
36 12534294 Phosphorylation of RGS14 by protein kinase A potentiates its activity toward G alpha i. 2003 Jan 28 1
37 12831845 Albumin: a Galpha(s)-specific guanine nucleotide dissociation inhibitor and GTPase activating protein. 2003 Jul 15 2
38 12860983 Oxidized human neuroglobin acts as a heterotrimeric Galpha protein guanine nucleotide dissociation inhibitor. 2003 Sep 19 1
39 14993354 The GoLoco motif: heralding a new tango between G protein signaling and cell division. 2002 Apr 3
40 11331068 Ggamma-like (GGL) domains: new frontiers in G-protein signaling and beta-propeller scaffolding. 2001 Jun 1 1
41 11344266 Mutant G protein alpha subunit activated by Gbeta gamma: a model for receptor activation? 2001 May 22 1
42 10852703 NMR structure of free RGS4 reveals an induced conformational change upon binding Galpha. 2000 Jun 20 1
43 10403517 Kinetic control of guanine nucleotide binding to soluble Galpha(q). 1999 Jul 1 3
44 10493878 Nucleotide-binding characteristics of human guanylate-binding protein 1 (hGBP1) and identification of the third GTP-binding motif. 1999 Sep 17 1
45 8611570 A 50 KDa protein modulates guanine nucleotide binding of transglutaminase II. 1996 Feb 27 2
46 7591763 [Mutation of G proteins]. 1995 Sep 1