Title : Structures of Gα Proteins in Complex with Their Chaperone Reveal Quality Control Mechanisms.

Pub. Date : 2020 Mar 17

PMID : 32126208






1 Functional Relationships(s)
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1 Here we show cryoEM structures of Galpha subunit folding intermediates in complex with full-length Ric-8A, a unique chaperone-client system in which substrate release is facilitated by guanine nucleotide binding to the client G protein. Guanine Nucleotides succinate-CoA ligase GDP/ADP-forming subunit alpha Homo sapiens