| 1 |
34102396 | Gain-of-function Tibetan PHD2D4E;C127S variant suppresses monocyte function: A lesson in inflammatory response to inspired hypoxia. | 2021 Jun |
2 |
| 2 |
32377332 | Genetic Analysis of EGLN1 C127S Variant in Taiwanese Parkinson's Disease. | 2020 |
1 |
| 3 |
29599405 | Transketolase Regulates the Metabolic Switch to Control Breast Cancer Cell Metastasis via the α-Ketoglutarate Signaling Pathway. | 2018 Jun 1 |
2 |
| 4 |
26740011 | Oxidative Dimerization of PHD2 is Responsible for its Inactivation and Contributes to Metabolic Reprogramming via HIF-1α Activation. | 2016 Jan 7 |
2 |
| 5 |
28163901 | Remote ischaemic preconditioning: closer to the mechanism? | 2016 |
1 |
| 6 |
25483211 | Lipophilic modification enhances anti-colitic properties of rosmarinic acid by potentiating its HIF-prolyl hydroxylases inhibitory activity. | 2015 Jan 15 |
1 |
| 7 |
25732824 | Metabolic reprogramming of cancer-associated fibroblasts by IDH3α downregulation. | 2015 Mar 3 |
2 |
| 8 |
25857330 | Increased Turnover at Limiting O2 Concentrations by the Thr(387) → Ala Variant of HIF-Prolyl Hydroxylase PHD2. | 2015 May 12 |
1 |
| 9 |
26713111 | Affinity-Based Fluorescence Polarization Assay for High-Throughput Screening of Prolyl Hydroxylase 2 Inhibitors. | 2015 Dec 10 |
2 |
| 10 |
25420025 | Intermediary metabolite precursor dimethyl-2-ketoglutarate stabilizes hypoxia-inducible factor-1α by inhibiting prolyl-4-hydroxylase PHD2. | 2014 |
1 |
| 11 |
27774468 | The role of PHD2 mutations in the pathogenesis of erythrocytosis. | 2014 |
1 |
| 12 |
23787140 | Substrate preference of the HIF-prolyl hydroxylase-2 (PHD2) and substrate-induced conformational change. | 2013 Sep |
1 |
| 13 |
22687491 | Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH). | 2012 Aug |
2 |
| 14 |
22747465 | Inverse solvent isotope effects demonstrate slow aquo release from hypoxia inducible factor-prolyl hydroxylase (PHD2). | 2012 Aug 21 |
1 |
| 15 |
21410436 | Biochemical characterization of human HIF hydroxylases using HIF protein substrates that contain all three hydroxylation sites. | 2011 Jun 1 |
1 |
| 16 |
20416277 | Hinokitiol activates the hypoxia-inducible factor (HIF) pathway through inhibition of HIF hydroxylases. | 2010 May 28 |
2 |
| 17 |
19498081 | Characterization of a robust enzymatic assay for inhibitors of 2-oxoglutarate-dependent hydroxylases. | 2009 Jul |
1 |
| 18 |
19775891 | 2-Oxoglutarate analogue inhibitors of prolyl hydroxylase domain 2. | 2009 Nov 1 |
4 |
| 19 |
16565084 | Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways. | 2006 Jun 2 |
1 |
| 20 |
16880998 | Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate. | 2005 Oct |
2 |