| 1 |
35415275 | Role of prolyl hydroxylase domain proteins in bone metabolism. | 2022 Mar |
1 |
| 2 |
35452683 | EGLN1 prolyl hydroxylation of hypoxia-induced transcription factor HIF1α is repressed by SET7-catalyzed lysine methylation. | 2022 Apr 20 |
3 |
| 3 |
33550096 | Alternative regulation of HIF-1α stability through Phosphorylation on Ser451. | 2021 Mar 19 |
1 |
| 4 |
33988258 | Inhibiting PHD2 in human periodontal ligament cells via lentiviral vector-mediated RNA interference facilitates cell osteogenic differentiation and periodontal repair. | 2021 Sep |
4 |
| 5 |
34137488 | Carbon Monoxide is an Inhibitor of HIF Prolyl Hydroxylase Domain 2. | 2021 Aug 3 |
1 |
| 6 |
31618435 | Prolyl Hydroxylase Inhibition Mitigates Pouchitis. | 2020 Jan 6 |
1 |
| 7 |
31852247 | PHD2 acts as an oncogene through activation of Ras/Raf/MEK/ERK and JAK1/STAT3 pathways in human hepatocellular carcinoma cells. | 2020 Dec |
1 |
| 8 |
31939292 | Mechanism of Molecular Oxygen Diffusion in a Hypoxia-Sensing Prolyl Hydroxylase Using Multiscale Simulation. | 2020 Feb 5 |
8 |
| 9 |
32377332 | Genetic Analysis of EGLN1 C127S Variant in Taiwanese Parkinson's Disease. | 2020 |
4 |
| 10 |
30719713 | Genetic variants at the EGLN1 locus associated with high-altitude adaptation in Tibetans are absent or found at low frequency in highland Andeans. | 2019 May |
3 |
| 11 |
30817904 | The roles and signaling pathways of prolyl-4-hydroxylase 2 in the tumor microenvironment. | 2019 Apr 25 |
5 |
| 12 |
30849228 | IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses In Vivo. | 2019 Jul 15 |
1 |
| 13 |
29530922 | Regulation of Hypoxia-Inducible Factor 1α during Hypoxia by DAP5-Induced Translation of PHD2. | 2018 Jun 1 |
2 |
| 14 |
29741264 | Genetic basis of congenital erythrocytosis. | 2018 May |
1 |
| 15 |
29772209 | Prolyl hydroxylase 2: a promising target to inhibit hypoxia-induced cellular metabolism in cancer cells. | 2018 Nov |
2 |
| 16 |
29917232 | PHD2 inactivation in Type I cells drives HIF-2α-dependent multilineage hyperplasia and the formation of paraganglioma-like carotid bodies. | 2018 Jun 19 |
2 |
| 17 |
29930174 | A HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia. | 2018 Aug |
1 |
| 18 |
29967369 | Osteocytic oxygen sensing controls bone mass through epigenetic regulation of sclerostin. | 2018 Jul 2 |
2 |
| 19 |
30411685 | Role of HIF-1 in Cancer Progression: Novel Insights. A Review. | 2018 |
1 |
| 20 |
30575721 | Loss of Phd2 cooperates with BRAFV600E to drive melanomagenesis. | 2018 Dec 21 |
2 |
| 21 |
27902963 | Homology modeling and molecular dynamics simulation of the HIF2α degradation-related HIF2α-VHL complex. | 2017 Jan |
2 |
| 22 |
28038470 | Hypoxia-inducible factor prolyl hydroxylase 2 (PHD2) is a direct regulator of epidermal growth factor receptor (EGFR) signaling in breast cancer. | 2017 Feb 7 |
4 |
| 23 |
28051298 | The Activity of JmjC Histone Lysine Demethylase KDM4A is Highly Sensitive to Oxygen Concentrations. | 2017 Apr 21 |
2 |
| 24 |
28199842 | The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia. | 2017 Feb 14 |
1 |
| 25 |
26082309 | Impairment of hypoxia-induced HIF-1α signaling in keratinocytes and fibroblasts by sulfur mustard is counteracted by a selective PHD-2 inhibitor. | 2016 May |
2 |
| 26 |
26740011 | Oxidative Dimerization of PHD2 is Responsible for its Inactivation and Contributes to Metabolic Reprogramming via HIF-1α Activation. | 2016 Jan 7 |
2 |
| 27 |
26754054 | Computational analysis of prolyl hydroxylase domain-containing protein 2 (PHD2) mutations promoting polycythemia insurgence in humans. | 2016 Jan 12 |
2 |
| 28 |
26951539 | Prolyl hydroxylase mediated inhibition of fatty acid synthase to combat tumor growth in mammary gland carcinoma. | 2016 Nov |
1 |
| 29 |
26972007 | The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A. | 2016 Mar 22 |
1 |
| 30 |
27019453 | Genomic insights into ayurvedic and western approaches to personalized medicine. | 2016 Mar |
1 |
| 31 |
27325674 | The Zinc Finger of Prolyl Hydroxylase Domain Protein 2 Is Essential for Efficient Hydroxylation of Hypoxia-Inducible Factor α. | 2016 Sep 15 |
3 |
| 32 |
27368101 | Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine. | 2016 Jun 30 |
1 |
| 33 |
27563096 | pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner. | 2016 Aug 26 |
1 |
| 34 |
28163901 | Remote ischaemic preconditioning: closer to the mechanism? | 2016 |
1 |
| 35 |
25809665 | Nuclear-cytoplasmatic shuttling of proteins in control of cellular oxygen sensing. | 2015 Jun |
1 |
| 36 |
25857330 | Increased Turnover at Limiting O2 Concentrations by the Thr(387) → Ala Variant of HIF-Prolyl Hydroxylase PHD2. | 2015 May 12 |
5 |
| 37 |
25936780 | NDRG3-mediated lactate signaling in hypoxia. | 2015 Jun |
1 |
| 38 |
26053282 | Metabolic aspects of high-altitude adaptation in Tibetans. | 2015 Nov |
1 |
| 39 |
26112411 | Kinetic Investigations of the Role of Factor Inhibiting Hypoxia-inducible Factor (FIH) as an Oxygen Sensor. | 2015 Aug 7 |
3 |
| 40 |
26235614 | The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts. | 2015 Aug 11 |
3 |
| 41 |
26498856 | The PHD2 oxygen sensor paves the way to metastasis. | 2015 Nov 3 |
1 |
| 42 |
26624507 | Prolyl-4-Hydroxylase 2 Potentially Contributes to Hepatocellular Carcinoma-Associated Erythrocytosis by Maintaining Hepatocyte Nuclear Factor-4α Expression. | 2015 |
1 |
| 43 |
24201705 | Human adaptation to the hypoxia of high altitude: the Tibetan paradigm from the pregenomic to the postgenomic era. | 2014 Apr 1 |
1 |
| 44 |
24468676 | Oxygen sensing strategies in mammals and bacteria. | 2014 Apr |
1 |
| 45 |
24711448 | Defective Tibetan PHD2 binding to p23 links high altitude adaption to altered oxygen sensing. | 2014 May 23 |
3 |
| 46 |
24761603 | [Hypoxia-responsive factor PHD2 and angiogenic diseases]. | 2014 Feb |
2 |
| 47 |
25010988 | Prolyl-4-hydroxylase 2 enhances hypoxia-induced glioblastoma cell death by regulating the gene expression of hypoxia-inducible factor-α. | 2014 Jul 10 |
2 |
| 48 |
25120187 | Investigating the contribution of the active site environment to the slow reaction of hypoxia-inducible factor prolyl hydroxylase domain 2 with oxygen. | 2014 Nov 1 |
4 |
| 49 |
25129147 | A genetic mechanism for Tibetan high-altitude adaptation. | 2014 Sep |
1 |
| 50 |
25431923 | Variants of the low oxygen sensors EGLN1 and HIF-1AN associated with acute mountain sickness. | 2014 Nov 26 |
3 |