Etoposide

cyclin dependent kinase inhibitor 1A ; Homo sapiens







35 Article(s)
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1 29372665 DNA methylation of the Oct4A enhancers in embryonal carcinoma cells after etoposide treatment is associated with alternative splicing and altered pluripotency in reversibly senescent cells. 2018 2
2 26625199 Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1. 2016 Jan 12 2
3 26102294 Role of stress-activated OCT4A in the cell fate decisions of embryonal carcinoma cells treated with etoposide. 2015 3
4 26506264 p21(WAF1) modulates drug-induced apoptosis and cell cycle arrest in B-cell precursor acute lymphoblastic leukemia. 2015 4
5 23287532 DNA damage causes TP53-dependent coupling of self-renewal and senescence pathways in embryonal carcinoma cells. 2013 Feb 1 1
6 23457546 EVI1 inhibits apoptosis induced by antileukemic drugs via upregulation of CDKN1A/p21/WAF in human myeloid cells. 2013 2
7 23272236 Sensitive detection and monitoring of senescence-associated secretory phenotype by SASP-RAP assay. 2012 2
8 21168391 Nucleoside analogs induce proteasomal down-regulation of p21 in chronic lymphocytic leukemia cell lines. 2011 Mar 1 1
9 21903579 p53-independent epigenetic repression of the p21(WAF1) gene in T-cell acute lymphoblastic leukemia. 2011 Oct 28 3
10 20226587 Potentiation of etoposide-induced apoptosis in HeLa cells by co-treatment with KG-135, a quality-controlled standardized ginsenoside formulation. 2010 Aug 1 4
11 19421231 Activation of p53 by MDM2 antagonists has differential apoptotic effects on Epstein-Barr virus (EBV)-positive and EBV-negative Burkitt's lymphoma cells. 2009 Sep 2
12 17252195 Cyclin-dependent protein kinase 2 activity is required for mitochondrial translocation of Bax and disruption of mitochondrial transmembrane potential during etoposide-induced apoptosis. 2007 Jul 6
13 17534580 Valproic acid induces p21 and topoisomerase-II (alpha/beta) expression and synergistically enhances etoposide cytotoxicity in human glioblastoma cell lines. 2007 Nov 2
14 16513841 Nuclear factor-kappaB dimer exchange promotes a p21(waf1/cip1) superinduction response in human T leukemic cells. 2006 Feb 1
15 16093994 Differential regulation of p21waf-1/cip-1 and Mdm2 by etoposide: etoposide inhibits the p53-Mdm2 autoregulatory feedback loop. 2005 Sep 2
16 14660614 The 31-kDa caspase-generated cleavage product of p130cas functions as a transcriptional repressor of E2A in apoptotic cells. 2004 Feb 27 3
17 15191662 [p33(ING1b) enhances chemosensitivity of osteosarcoma cell U2OS to etoposide]. 2004 Jun 2
18 12767922 P21 response to DNA damage induced by genistein and etoposide in human lung cancer cells. 2003 Jun 13 13
19 15314975 Expression of p21 and bcl-2 proteins in paraffin-embedded preparations of non-small cell lung cancer in stage IIIA after Etoposide and Cisplatin induced chemotherapy. 2003 1
20 11821415 ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53. 2002 Apr 12 1
21 12429914 The cyclin-dependent kinase inhibitor butyrolactone is a potent inhibitor of p21 (WAF1/CIP1 expression). 2002 Jan 1
22 12513833 [p21(WAF1) transfection decreases sensitivity of K562 cells to VP-16]. 2002 Feb 2
23 12553001 DNA topoisomerase II inhibitor, etoposide, induces p21WAF1/CIP1 through down-regulation of c-Myc in K562 cells. 2002 Nov-Dec 4
24 11423989 p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents. 2001 Jun 7 1
25 11005251 Identification and characterization of genes responsive to apoptosis: application of DNA chip technology and mRNA differential display. 2000 Oct 2
26 11045764 Adenoviral-mediated gene therapy with Ad5CMVp53 and Ad5CMVp21 in combination with standard therapies in human breast cancer cell lines. 2000 Oct 1
27 11062729 Concentration-dependent variable effects of etoposide on the cell cycle of CML cells. 2000 Sep-Oct 4
28 10023685 Differential regulation of p21waf-1/cip-1 and Mdm2 by etoposide: etoposide inhibits the p53-Mdm2 autoregulatory feedback loop. 1999 Jan 28 2
29 10218124 Cytoprotective effects of hematopoietic growth factors on primary human acute myeloid leukemias are not mediated through changes in BCL-2, bax, or p21WAF1/CIP1. 1999 Jan-Feb 1
30 9687575 Involvement of the mismatch repair system in temozolomide-induced apoptosis. 1998 Aug 1
31 9739169 DNA damage induces p21 protein expression by inhibiting ubiquitination in ML-1 cells. 1998 Sep 16 4
32 9054953 Potentiation of etoposide-induced apoptosis by staurosporine in human tumor cells is associated with events downstream of DNA-protein complex formation. 1997 1
33 14646555 Serum withdrawal and etoposide induce apoptosis in human lung carcinoma cell line A549 via distinct pathways. 1997 2
34 8620501 Hypersensitivity of human testicular tumors to etoposide-induced apoptosis is associated with functional p53 and a high Bax:Bcl-2 ratio. 1996 Apr 15 1
35 7970699 Mechanisms of regulation of WAF1/Cip1 gene expression in human breast carcinoma: role of p53-dependent and independent signal transduction pathways. 1994 Dec 4