Pub. Date : 2002 Nov-Dec
PMID : 12553001
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | DNA topoisomerase II inhibitor, etoposide, induces p21WAF1/CIP1 through down-regulation of c-Myc in K562 cells. | Etoposide | cyclin dependent kinase inhibitor 1A | Homo sapiens |
| 2 | To investigate the mechanism by which etoposide acts as an anticancer agent, the relationship between p21WAF1/CIP1 (p21) and c-Myc was studied. | Etoposide | cyclin dependent kinase inhibitor 1A | Homo sapiens |
| 3 | To investigate the mechanism by which etoposide acts as an anticancer agent, the relationship between p21WAF1/CIP1 (p21) and c-Myc was studied. | Etoposide | cyclin dependent kinase inhibitor 1A | Homo sapiens |
| 4 | Etoposide activated the p21 promoter in a concentration-dependent manner, and etoposide-induced luciferase activity was suppressed by co-transfection of c-Myc. | Etoposide | cyclin dependent kinase inhibitor 1A | Homo sapiens |