trichostatin A

cyclin dependent kinase inhibitor 1A ; Homo sapiens







77 Article(s)
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1 33576217 Effect of Valproic Acid on the Class I Histone Deacetylase 1, 2 and 3, Tumor Suppressor Genes p21WAF1/CIP1 and p53, and Intrinsic Mitochondrial Apoptotic Pathway, Pro- (Bax, Bak, and Bim) and anti- (Bcl-2, Bcl-xL, and Mcl-1) Apoptotic Genes Expression, Cell Viability, and Apoptosis Induction in Hepatocellular Carcinoma HepG2 Cell Line. 2021 Feb 1 4
2 33649777 HDAC inhibitors suppress the proliferation, migration and invasiveness of human head and neck squamous cell carcinoma cells via p63‑mediated tight junction molecules and p21‑mediated growth arrest. 2021 Apr 1
3 31913698 Impact of the histone deacetylase inhibitor trichostatin A on active uptake, volume-sensitive release of taurine, and cell fate in human ovarian cancer cells. 2020 Mar 1 2
4 32592383 Investigation of the Effect of Zebularine in Comparison to and in Combination with Trichostatin A on p21Cip1/Waf1/ Sdi1, p27Kip1, p57Kip2, DNA Methyltransferases and Histone Deacetylases in Colon Cancer LS 180 Cell Line. 2020 Jun 1 3
5 30902084 Short-term stimulation with histone deacetylase inhibitor trichostatin a induces epithelial-mesenchymal transition in nasopharyngeal carcinoma cells without increasing cell invasion ability. 2019 Mar 22 1
6 31516890 Effect of 5-Aza-2'-Deoxycytidine in Comparison to Valproic Acid and Trichostatin A on Histone Deacetylase 1, DNA Methyltransferase 1, and CIP/KIP Family (p21, p27, and p57) Genes Expression, Cell Growth Inhibition, and Apoptosis Induction in Colon Cancer SW480 Cell Line. 2019 1
7 30214285 Trichostatin A promotes GLI1 degradation and P21 expression in multiple myeloma cells. 2018 3
8 30334455 Trichostatin A inhibits proliferation of triple negative breast cancer cells by inducing cell cycle arrest and apoptosis. 2018 Nov 15 1
9 28393191 Inactivation of EGFR/AKT signaling enhances TSA-induced ovarian cancer cell differentiation. 2017 May 1
10 24030871 Inhibition of mTOR signalling potentiates the effects of trichostatin A in human gastric cancer cell lines by promoting histone acetylation. 2014 Jan 2
11 24456602 Trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial-mesenchymal transition in retinal pigment epithelium cells. 2014 Apr 2
12 24639460 P21-driven multifusion gene system for evaluating the efficacy of histone deacetylase inhibitors by in vivo molecular imaging and for transcription targeting therapy of cancer mediated by histone deacetylase inhibitor. 2014 Apr 1
13 24668547 Differential expression of histone deacetylase and acetyltransferase genes in gastric cancer and their modulation by trichostatin A. 2014 Jul 1
14 23745024 Mechanisms of trichostatin A inhibiting AGS proliferation and identification of lysine-acetylated proteins. 2013 Jun 7 2
15 24157878 The epigenetic modifier trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial-mesenchymal transition of lens epithelial cells. 2013 Oct 24 2
16 22006862 Plant flavone apigenin inhibits HDAC and remodels chromatin to induce growth arrest and apoptosis in human prostate cancer cells: in vitro and in vivo study. 2012 Dec 1
17 22114073 Green tea polyphenols causes cell cycle arrest and apoptosis in prostate cancer cells by suppressing class I histone deacetylases. 2012 Feb 1
18 22270849 P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells. 2012 May 8
19 22277651 Ligand-dependent corepressor (LCoR) recruitment by Kruppel-like factor 6 (KLF6) regulates expression of the cyclin-dependent kinase inhibitor CDKN1A gene. 2012 Mar 16 1
20 22341071 Histone deacetylase inhibitors induced differentiation and accelerated mineralization of pulp-derived cells. 2012 Mar 1
21 22781708 ERK inhibition enhances TSA-induced gastric cancer cell apoptosis via NF-κB-dependent and Notch-independent mechanism. 2012 Sep 4 6
22 24280698 Differential cellular and molecular effects of butyrate and trichostatin a on vascular smooth muscle cells. 2012 Sep 4 3
23 21519790 Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells. 2011 Jul 3
24 25961258 Liposomal trichostatin A: therapeutic potential in hormone-dependent and -independent breast cancer xenograft models. 2011 May 1 1
25 20178884 Immunohistochemical detection of histone deacetylases in endometrial carcinoma: involvement of histone deacetylase 2 in the proliferation of endometrial carcinoma cells. 2010 Jun 1
26 20419833 Molecular determinants of the antitumor effects of trichostatin A in pancreatic cancer cells. 2010 Apr 28 4
27 19270532 Sensitization to gamma-irradiation-induced cell cycle arrest and apoptosis by the histone deacetylase inhibitor trichostatin A in non-small cell lung cancer (NSCLC) cells. 2009 May 2
28 19275888 p21(WAF1) negatively regulates DNMT1 expression in mammalian cells. 2009 Apr 24 2
29 19697617 Histone deacetylase inhibitor trichostatin A modulates cell cycles in A2780 human ovarian cancer cell lines. 2009 2
30 18097580 Cell cycle arrest and lytic induction of EBV-transformed B lymphoblastoid cells by a histone deacetylase inhibitor, Trichostatin A. 2008 Jan 2
31 18206478 The efficacy of combination therapy using adeno-associated virus--interferon beta and trichostatin A in vitro and in a murine model of neuroblastoma. 2008 Jan 2
32 18644983 Modulation of the cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by Zac1 through the antagonistic regulators p53 and histone deacetylase 1 in HeLa Cells. 2008 Jul 6
33 17239344 p21waf1/Cip1 partially mediates apoptosis in hepatocellular carcinoma cells. 2007 Mar 9 4
34 17481908 CD81, a cell cycle regulator, is a novel target for histone deacetylase inhibition in glioma cells. 2007 Jun 3
35 17650409 [Experimental study on the effect of trichostatin A on differentiation of human lung carcinoma cell]. 2007 Apr 3 2
36 17669439 Inhibition of telomerase activity and human telomerase reverse transcriptase gene expression by histone deacetylase inhibitor in human brain cancer cells. 2007 Dec 1 1
37 16009488 SK-7041, a new histone deacetylase inhibitor, induces G2-M cell cycle arrest and apoptosis in pancreatic cancer cell lines. 2006 Jun 8 1
38 16280330 Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells. 2006 Apr 2
39 16284094 Trichostatin A sensitises rheumatoid arthritis synovial fibroblasts for TRAIL-induced apoptosis. 2006 Jul 2
40 16488717 Effectiveness of trichostatin A as a potential candidate for anticancer therapy in non-small-cell lung cancer. 2006 Mar 1
41 16755652 Trichostatin A cooperates with Fas-mediated signal to induce apoptosis in rheumatoid arthritis synovial fibroblasts. 2006 Jun 3
42 16865256 Histone deacetylase inhibitor, trichostatin A, increases the chemosensitivity of anticancer drugs in gastric cancer cell lines. 2006 Sep 2
43 16886664 Epigenetic corruption of VDR signalling in malignancy. 2006 Jul-Aug 1
44 15586362 Histone H3 acetylation is associated with reduced p21(WAF1/CIP1) expression by gastric carcinoma. 2005 Jan 2
45 15854272 [The mechanisms of p21WAF1/Cip-1 expression in MOLT-4 cell line induced by TSA]. 2005 Apr 19
46 16026644 Interactive effects of HDAC inhibitors and TRAIL on apoptosis are associated with changes in mitochondrial functions and expressions of cell cycle regulatory genes in multiple myeloma. 2005 Jul 2
47 15059516 [Regulation of histone acetylation on the expression of cell cycle-associated genes in human colon cancer cell lines]. 2004 Feb 17 4
48 15107822 Histone deacetylase inhibitors activate INK4d gene through Sp1 site in its promoter. 2004 Jul 8 2
49 15179185 Deacetylase inhibition in malignant melanomas: impact on cell cycle regulation and survival. 2004 Jun 5
50 15474507 Histone deacetylase inhibitor, Trichostatin A, activates p21WAF1/CIP1 expression through downregulation of c-myc and release of the repression of c-myc from the promoter in human cervical cancer cells. 2004 Nov 12 5