Irinotecan

UDP glucuronosyltransferase family 1 member A7 ; Homo sapiens







14 Article(s)
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1 27895797 UGT1A1*6, UGT1A7*3 and UGT1A9*1b polymorphisms are predictive markers for severe toxicity in patients with metastatic gastrointestinal cancer treated with irinotecan-based regimens. 2016 Nov 1
2 24834123 Polymorphisms of uridine glucuronosyltransferase gene and irinotecan toxicity: low dose does not protect from toxicity. 2014 1
3 23303296 Polymorphisms of the UDP-glucuronosyl transferase 1A genes are associated with adverse events in cancer patients receiving irinotecan-based chemotherapy. 2013 Feb 1
4 23789755 [Influence of genetic polymorphisms in UGT1A1, UGT1A7 and UGT1A9 on the pharmacokynetics of irinotecan, SN-38 and SN-38G]. 2013 Mar-Apr 5
5 24033692 UGT1A1*6, 1A7*3, and 1A9*22 genotypes predict severe neutropenia in FOLFIRI-treated metastatic colorectal cancer in two prospective studies in Japan. 2013 Dec 1
6 18349289 Gilbert's Syndrome and irinotecan toxicity: combination with UDP-glucuronosyltransferase 1A7 variants increases risk. 2008 Mar 9
7 18418374 Pharmacogenetic pathway analysis of irinotecan. 2008 Sep 6
8 17406868 Genetic linkage of UGT1A7 and UGT1A9 polymorphisms to UGT1A1*6 is associated with reduced activity for SN-38 in Japanese patients with cancer. 2007 Sep 3
9 15709193 UGT1A7 and UGT1A9 polymorphisms predict response and toxicity in colorectal cancer patients treated with capecitabine/irinotecan. 2005 Feb 1 2
10 15716465 Identification and characterization of a functional TATA box polymorphism of the UDP glucuronosyltransferase 1A7 gene. 2005 May 2
11 12730278 Functional characterization of human UDP-glucuronosyltransferase 1A9 variant, D256N, found in Japanese cancer patients. 2003 Aug 2
12 12036456 Genetic polymorphisms of the UDP-glucuronosyltransferase 1A7 gene and irinotecan toxicity in Japanese cancer patients. 2002 May 1
13 12181437 Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38). 2002 Sep 1
14 10381366 Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38) by the human UDP-glucuronosyltransferases encoded at the UGT1 locus. 1999 Jun 24 1