Cyclic AMP

prostaglandin E receptor 2 (subtype EP2) ; Mus musculus







48 Article(s)
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1 33786738 The differential functional coupling of phosphodiesterase 4 to human DP and EP2 prostanoid receptors stimulated with PGD2 or PGE2. 2021 Jun 1
2 31934812 Effects of the Selective EP2 Receptor Agonist Omidenepag on Adipocyte Differentiation in 3T3-L1 Cells. 2020 Apr 1
3 32820026 PGE2 accounts for bidirectional changes in alveolar macrophage self-renewal with aging and smoking. 2020 Nov 2
4 28589946 Elevated prostaglandin E2 post-bone marrow transplant mediates interleukin-1β-related lung injury. 2018 Mar 4
5 29746568 The protective effect of the EP2 receptor on TGF-β1 induced podocyte injury via the PI3K / Akt signaling pathway. 2018 1
6 28062696 Prostaglandin E2 Inhibition of IL-27 Production in Murine Dendritic Cells: A Novel Mechanism That Involves IRF1. 2017 Feb 15 1
7 28341741 Endogenous prostaglandin E2 amplifies IL-33 production by macrophages through an E prostanoid (EP)2/EP4-cAMP-EPAC-dependent pathway. 2017 May 19 1
8 28842681 Cyclooxygenase-2 contributes to oxidopamine-mediated neuronal inflammation and injury via the prostaglandin E2 receptor EP2 subtype. 2017 Aug 25 1
9 27558562 The vasopressin type 2 receptor and prostaglandin receptors EP2 and EP4 can increase aquaporin-2 plasma membrane targeting through a cAMP-independent pathway. 2016 Nov 1 3
10 25451967 Neuroprotective role of prostaglandin PGE2 EP2 receptor in hemin-mediated toxicity. 2015 Jan 1
11 25614334 Inhibition of P2Y6 receptor-mediated phospholipase C activation and Ca(2+) signalling by prostaglandin E2 in J774 murine macrophages. 2015 Feb 15 3
12 25049356 Prostaglandin E2 negatively regulates the production of inflammatory cytokines/chemokines and IL-17 in visceral leishmaniasis. 2014 Sep 1 1
13 25327961 Role of the prostaglandin E2/E-prostanoid 2 receptor signalling pathway in TGFβ-induced mice mesangial cell damage. 2014 Dec 12 1
14 23064451 Prostaglandin E(2) inhibits proteinase-activated receptor 2-signal transduction through regulation of receptor internalization. 2013 3
15 21761157 Frondoside A inhibits breast cancer metastasis and antagonizes prostaglandin E receptors EP4 and EP2. 2012 Apr 1
16 22159280 EP2 and EP4 receptors on muscularis resident macrophages mediate LPS-induced intestinal dysmotility via iNOS upregulation through cAMP/ERK signals. 2012 Mar 1 1
17 22420773 Prostaglandin E₂ maintains mouse ESC undifferentiated state through regulation of connexin31, connexin43 and connexin45 expression: involvement of glycogen synthase kinase 3β/β-catenin. 2012 Jul 1
18 22503965 Prostaglandin E2 stimulates cystogenesis through EP4 receptor in IMCD-3 cells. 2012 May 1
19 21298000 Prostaglandin E2 reverses aberrant production of an inflammatory chemokine by microglia from Sandhoff disease model mice through the cAMP-PKA pathway. 2011 Jan 27 1
20 21835766 A major role for the EP4 receptor in regulation of renin. 2011 Nov 1
21 20051652 Prostaglandin E2, an immunoactivator. 2010 1
22 21040553 Mammalian oocytes are targets for prostaglandin E2 (PGE2) action. 2010 Nov 1 1
23 19635910 E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection. 2009 Aug 15 1
24 19712723 Expression of cyclooxygenase-1/-2, microsomal prostaglandin-E synthase-1 and E-prostanoid receptor 2 and regulation of inflammatory mediators by PGE(2) in the amoeboid microglia in hypoxic postnatal rats and murine BV-2 cells. 2009 Dec 15 2
25 18456799 Paradoxical role of alveolar macrophage-derived granulocyte-macrophage colony-stimulating factor in pulmonary host defense post-bone marrow transplantation. 2008 Jul 1
26 18820644 TLR4/MYD88-dependent, LPS-induced synthesis of PGE2 by macrophages or dendritic cells prevents anti-CD3-mediated CD95L upregulation in T cells. 2008 Dec 1
27 16540639 Prostaglandin E receptor EP4 antagonism inhibits breast cancer metastasis. 2006 Mar 15 2
28 16607275 Overexpression of the prostaglandin E2 receptor EP2 results in enhanced skin tumor development. 2006 Sep 7 1
29 15797843 PGE2 enhances cytokine-elicited nitric oxide production in mouse cortical collecting duct cells. 2005 May 1
30 15836955 Ovulation: new factors that prepare the oocyte for fertilization. 2005 Apr 29 1
31 15843564 Bleomycin-induced E prostanoid receptor changes alter fibroblast responses to prostaglandin E2. 2005 May 1 1
32 15930264 The prostaglandin E2 receptor EP2 is required for cyclooxygenase 2-mediated mammary hyperplasia. 2005 Jun 1 5
33 16230392 Lack of expression of the EP2 but not EP3 receptor for prostaglandin E2 results in suppression of skin tumor development. 2005 Oct 15 1
34 12939279 Effects of mechanical strain on the function of Gap junctions in osteocytes are mediated through the prostaglandin EP2 receptor. 2003 Oct 31 1
35 12959984 Disrupted function of tumor necrosis factor-alpha-stimulated gene 6 blocks cumulus cell-oocyte complex expansion. 2003 Oct 1
36 14577329 [Cooperation of two subtypes of PGE2 receptor, Gi coupled EP3 and Gs coupled EP2 or EP4 subtype]. 2003 Oct 1
37 12013525 Prostaglandin receptor EP2 mediates PGE2 stimulated hypercalcemia in mice in vivo. 2002 Apr 1
38 12184998 Prostaglandins that increase renin production in response to ACE inhibition are not derived from cyclooxygenase-1. 2002 Sep 1
39 11181968 G protein-coupled prostanoid receptors and the kidney. 2001 2
40 11237479 Mechanisms involved in prostaglandin-induced increase in bone resorption in neonatal mouse calvaria. 2001 Feb 1
41 11338379 [Role of EP4 receptor in bone resorption induced by PGE]. 2001 Apr 1
42 11502472 Bone biomechanical properties in prostaglandin EP1 and EP2 knockout mice. 2001 Aug 2
43 10654821 Prostaglandin receptors: their role in regulating renal function. 2000 Jan 2
44 10731717 Suppression of prostaglandin E(2)-mediated c-fos mRNA induction by interleukin-4 in murine macrophages. 2000 Mar 1
45 10746663 The role of prostaglandin E receptor subtypes (EP1, EP2, EP3, and EP4) in bone resorption: an analysis using specific agonists for the respective EPs. 2000 Apr 3
46 11036222 Prostaglandin E(2) enhances axonal transport and neuritogenesis in cultured mouse dorsal root ganglion neurons. 2000 1
47 11071876 Prostaglandin E(2) receptors, EP2 and EP4, differentially modulate TNF-alpha and IL-6 production induced by lipopolysaccharide in mouse peritoneal neutrophils. 2000 Nov 11 1
48 8855294 Prostaglandin E2 receptors of the EP2 and EP4 subtypes regulate activation and differentiation of mouse B lymphocytes to IgE-secreting cells. 1996 Oct 1 2