Serine

NFKB inhibitor alpha ; Homo sapiens







142 Article(s)
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1 33808757 Attribution of NF-κB Activity to CHUK/IKKα-Involved Carcinogenesis. 2021 Mar 19 2
2 34030642 Co-relation with novel phosphorylation sites of IκBα and necroptosis in breast cancer cells. 2021 May 24 1
3 34224210 Dynamic chromatin association of IκBα is regulated by acetylation and cleavage of histone H4. 2021 Aug 4 2
4 31683054 A novel NFKBIA variant substituting serine 36 of IκBα causes immunodeficiency with warts, bronchiectasis and juvenile rheumatoid arthritis in the absence of ectodermal dysplasia. 2020 Jan 4
5 30804118 Pentoxifylline Enhances the Apoptotic Effect of Carboplatin in Y79 Retinoblastoma Cells. 2019 Mar-Apr 1
6 30819886 NF-κB activation is a turn on for vaccinia virus phosphoprotein A49 to turn off NF-κB activation. 2019 Mar 19 1
7 31125555 A novel specific cleavage of IκBα protein in acute myeloid leukemia cells involves protease PR3. 2019 Sep 1 1
8 28431901 Clozapine reduces Toll-like receptor 4/NF-κB-mediated inflammatory responses through inhibition of calcium/calmodulin-dependent Akt activation in microglia. 2018 Feb 2 1
9 28629746 Mechanisms of genotype-phenotype correlation in autosomal dominant anhidrotic ectodermal dysplasia with immune deficiency. 2018 Mar 1
10 28597146 Human IκBα Gain of Function: a Severe and Syndromic Immunodeficiency. 2017 Jul 1
11 26910425 Binding of NFκB Appears to Twist the Ankyrin Repeat Domain of IκBα. 2016 Feb 23 2
12 27098354 Selective activation of TNFR1 and NF-κB inhibition by a novel biyouyanagin analogue promotes apoptosis in acute leukemia cells. 2016 Apr 20 1
13 27339895 Role of WW Domain-containing Oxidoreductase WWOX in Driving T Cell Acute Lymphoblastic Leukemia Maturation. 2016 Aug 12 1
14 25881508 GRK6 phosphorylates IκBα at Ser(32)/Ser(36) and enhances TNF-α-induced inflammation. 2015 May 29 4
15 26246800 Dimethylfumarate protects against TNF-α-induced secretion of inflammatory cytokines in human endothelial cells. 2015 1
16 24552816 Distinctive effects of the cellular inhibitor of apoptosis protein c-IAP2 through stabilization by XIAP in glioblastoma multiforme cells. 2014 1
17 25267645 IKK phosphorylates RelB to modulate its promoter specificity and promote fibroblast migration downstream of TNF receptors. 2014 Oct 14 1
18 23250755 Phosphorylation of IκBα at serine 32 by T-lymphokine-activated killer cell-originated protein kinase is essential for chemoresistance against doxorubicin in cervical cancer cells. 2013 Feb 1 2
19 23468625 Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence. 2013 Feb 2
20 23892407 Doxorubicin induces atypical NF-κB activation through c-Abl kinase activity in breast cancer cells. 2013 Oct 1
21 24083678 Sulindac activates NF-κB signaling in colon cancer cells. 2013 Oct 1 1
22 22139346 Vitamin E ameliorates ox-LDL-induced foam cells formation through modulating the activities of oxidative stress-induced NF-κB pathway. 2012 Apr 1
23 22847000 Curcumin inhibits Rift Valley fever virus replication in human cells. 2012 Sep 28 1
24 22849569 Increased expression of the homologue of enhancer-of-split 1 protects neurons from beta amyloid neurotoxicity and hints at an alternative role for transforming growth factor beta1 as a neuroprotector. 2012 Jul 31 1
25 22896603 U20 is responsible for human herpesvirus 6B inhibition of tumor necrosis factor receptor-dependent signaling and apoptosis. 2012 Nov 1
26 20890592 Acrolein, an I-κBα-independent downregulator of NF-κB activity, causes the decrease in nitric oxide production in human malignant keratinocytes. 2011 May 1
27 21220295 Detection of a ternary complex of NF-kappaB and IkappaBalpha with DNA provides insights into how IkappaBalpha removes NF-kappaB from transcription sites. 2011 Jan 25 3
28 21700900 Specific effects of BCL10 Serine mutations on phosphorylations in canonical and noncanonical pathways of NF-κB activation following carrageenan. 2011 Sep 1
29 20191354 N-nitroso-N-methylurea and N-nitroso-N-ethylurea induce upregulation of cellular NF-kappa B activity through protein kinase C-dependent pathway in human malignant keratinocytes. 2010 Jan 1
30 20385620 RSK2 mediates NF-{kappa}B activity through the phosphorylation of IkappaBalpha in the TNF-R1 pathway. 2010 Sep 2
31 20450893 Tyrosine phosphatase inhibition triggers sustained canonical serine-dependent NFkappaB activation via Src-dependent blockade of PP2A. 2010 Aug 15 1
32 18444250 Betulinic acid suppresses constitutive and TNFalpha-induced NF-kappaB activation and induces apoptosis in human prostate carcinoma PC-3 cells. 2008 Dec 1
33 18453612 Dual role of NOX2 in respiratory syncytial virus- and sendai virus-induced activation of NF-kappaB in airway epithelial cells. 2008 May 15 1
34 18455150 Geldanamycin inhibits tyrosine phosphorylation-dependent NF-kappaB activation. 2008 Jun 1 1
35 18468507 Proteasome inhibitors induce apoptosis of prostate cancer cells by inducing nuclear translocation of IkappaBalpha. 2008 Jul 15 1
36 18474597 Hydrogen peroxide prolongs nuclear localization of NF-kappaB in activated cells by suppressing negative regulatory mechanisms. 2008 Jul 4 1
37 18657515 The human IKKbeta subunit kinase domain displays CK2-like phosphorylation specificity. 2008 Sep 26 4
38 17454143 [6]-Gingerol prevents UVB-induced ROS production and COX-2 expression in vitro and in vivo. 2007 May 1
39 17928537 Histamine enhances the production of human beta-defensin-2 in human keratinocytes. 2007 Dec 1
40 18056447 Traf1 induction and protection from tumor necrosis factor by nuclear factor-kappaB p65 is independent of serine 536 phosphorylation. 2007 Dec 1 1
41 15695387 Antiapoptotic effect of serum and glucocorticoid-inducible protein kinase is mediated by novel mechanism activating I{kappa}B kinase. 2005 Jan 15 1
42 15880609 EGFR and Her-2 regulate the constitutive activation of NF-kappaB in PC-3 prostate cancer cells. 2005 Oct 1 2
43 15893541 Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFkappaB activation and cyclin D1 up-regulation. 2005 Jun 1 1
44 15899834 1'-acetoxychavicol acetate is a novel nuclear factor kappaB inhibitor with significant activity against multiple myeloma in vitro and in vivo. 2005 May 15 1
45 15950427 Chemokine IL-8 induction by particulate wear debris in osteoblasts is mediated by NF-kappaB. 2005 Nov 1
46 16007147 Betulinic acid as new activator of NF-kappaB: molecular mechanisms and implications for cancer therapy. 2005 Oct 20 1
47 16015604 Independent role of phosphoinositol-3-kinase (PI3K) and casein kinase II (CK-2) in EGFR and Her-2-mediated constitutive NF-kappaB activation in prostate cancer cells. 2005 Dec 1 1
48 16105840 Phosphorylation of RelA/p65 on serine 536 defines an I{kappa}B{alpha}-independent NF-{kappa}B pathway. 2005 Oct 14 1
49 16195219 Inhibition of SRC tyrosine kinases suppresses activation of nuclear factor-kappaB, and serine and tyrosine phosphorylation of IkappaB-alpha in lipopolysaccharide-stimulated raw 264.7 macrophages. 2005 Oct 8 1
50 15128824 Transient and selective NF-kappa B p65 serine 536 phosphorylation induced by T cell costimulation is mediated by I kappa B kinase beta and controls the kinetics of p65 nuclear import. 2004 May 15 3