| 1 |
35602653 | Disruption of cellular iron homeostasis by IREB2 missense variants causes severe neurodevelopmental delay, dystonia and seizures. | 2022 |
6 |
| 2 |
33393230 | The deubiquitinase OTUD1 enhances iron transport and potentiates host antitumor immunity. | 2021 Feb 3 |
2 |
| 3 |
34039609 | Iron-sulfur cluster deficiency can be sensed by IRP2 and regulates iron homeostasis and sensitivity to ferroptosis independent of IRP1 and FBXL5. | 2021 May |
3 |
| 4 |
34064225 | Hereditary Hyperferritinemia Cataract Syndrome: Ferritin L Gene and Physiopathology behind the Disease-Report of New Cases. | 2021 May 21 |
2 |
| 5 |
34389108 | Mechanisms of cellular iron sensing, regulation of erythropoiesis and mitochondrial iron utilization. | 2021 Jul |
4 |
| 6 |
34462321 | Paralogous synthetic lethality underlies genetic dependencies of the cancer-mutated gene STAG2. | 2021 Nov |
1 |
| 7 |
34573347 | Conservation in the Iron Responsive Element Family. | 2021 Aug 30 |
2 |
| 8 |
31907996 | Mdm2 is a target and mediator of IRP2 in cell growth control. | 2020 Feb |
2 |
| 9 |
31941883 | Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification. | 2020 Jan 15 |
4 |
| 10 |
32112499 | Relieving ferroptosis may partially reverse neurodegeneration of the auditory cortex. | 2020 Nov |
1 |
| 11 |
32126207 | FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster. | 2020 Apr 2 |
7 |
| 12 |
32243827 | How Oxidation of a Unique Iron-Sulfur Cluster in FBXL5 Regulates IRP2 Levels and Promotes Regulation of Iron Metabolism Proteins. | 2020 Apr 2 |
3 |
| 13 |
32276991 | Iron Regulatory Protein 2 Exerts its Oncogenic Activities by Suppressing TAp63 Expression. | 2020 Jul |
2 |
| 14 |
32377332 | Genetic Analysis of EGLN1 C127S Variant in Taiwanese Parkinson's Disease. | 2020 |
2 |
| 15 |
32564977 | Basics and principles of cellular and systemic iron homeostasis. | 2020 Oct |
1 |
| 16 |
33295723 | Is serum iron responsive protein-2 level associated with pulmonary functions and frequent exacerbator phenotype in COPD? | 2020 Sep |
3 |
| 17 |
30218771 | Regulation of cellular iron metabolism: Iron-dependent degradation of IRP by SCFFBXL5 ubiquitin ligase. | 2019 Mar |
1 |
| 18 |
30449675 | Perturbation of Iron Metabolism by Cisplatin through Inhibition of Iron Regulatory Protein 2. | 2019 Jan 17 |
4 |
| 19 |
30760976 | Oxidative Stress Regulated Iron Regulatory Protein IRP2 Through FBXL5-Mediated Ubiquitination-Proteasome Way in SH-SY5Y Cells. | 2019 |
8 |
| 20 |
30915432 | Absence of iron-responsive element-binding protein 2 causes a novel neurodegenerative syndrome. | 2019 May 1 |
1 |
| 21 |
31076252 | Delta-aminolevulinic acid synthase 2 expression in combination with iron as modifiers of disease severity in erythropoietic protoporphyria. | 2019 Nov |
2 |
| 22 |
31092704 | Zinc induces iron uptake and DMT1 expression in Caco-2 cells via a PI3K/IRP2 dependent mechanism. | 2019 Jun 11 |
2 |
| 23 |
31220756 | Specific heme binding to heme regulatory motifs in iron regulatory proteins and its functional significance. | 2019 Sep |
2 |
| 24 |
29449016 | Redox-dependent axial ligand replacement and its functional significance in heme-bound iron regulatory proteins. | 2018 May |
1 |
| 25 |
29572489 | Iron regulatory protein deficiency compromises mitochondrial function in murine embryonic fibroblasts. | 2018 Mar 23 |
3 |
| 26 |
29652073 | The iron regulatory proteins are defective in repressing translation via exogenous 5' iron responsive elements despite their relative abundance in leukemic cellular models. | 2018 Apr 25 |
3 |
| 27 |
27794191 | Modulation of iron transport, metabolism and reactive oxygen status by quercetin-iron complexes in vitro. | 2017 Mar |
1 |
| 28 |
28031527 | Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism. | 2017 Jan 24 |
1 |
| 29 |
28131773 | Redox sensing molecular mechanism of an iron metabolism regulatory protein FBXL5. | 2017 Feb 15 |
1 |
| 30 |
28166223 | Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective. | 2017 Feb |
3 |
| 31 |
28281325 | BRAF mutations are associated with increased iron regulatory protein-2 expression in colorectal tumorigenesis. | 2017 Jun |
2 |
| 32 |
28387022 | Systemic iron homeostasis and erythropoiesis. | 2017 Jun |
1 |
| 33 |
28404645 | IRP2 as a potential modulator of cell proliferation, apoptosis and prognosis in nonsmall cell lung cancer. | 2017 Apr |
5 |
| 34 |
28450115 | Iron regulatory protein 2 in ovarian endometrial cysts. | 2017 Jun 10 |
6 |
| 35 |
28453699 | MicroRNA-related genetic variants in iron regulatory genes, dietary iron intake, microRNAs and lung cancer risk. | 2017 May 1 |
2 |
| 36 |
28638917 | Influence of sodium nitroprusside on expressions of FBXL5 and IRP2 in SH-SY5Y cells. | 2017 Jun 25 |
2 |
| 37 |
28768766 | A synergistic role of IRP1 and FBXL5 proteins in coordinating iron metabolism during cell proliferation. | 2017 Sep 22 |
3 |
| 38 |
28775066 | The interplay between iron and oxygen homeostasis with a particular focus on the heart. | 2017 Oct 1 |
2 |
| 39 |
28939752 | Checks and balances for the iron bank. | 2017 Sep 22 |
2 |
| 40 |
29061112 | Iron regulatory protein (IRP)-iron responsive element (IRE) signaling pathway in human neurodegenerative diseases. | 2017 Oct 23 |
1 |
| 41 |
29070551 | Current understanding of iron homeostasis. | 2017 Dec |
1 |
| 42 |
29137259 | Iron-responsive element-binding protein 2 plays an essential role in regulating prostate cancer cell growth. | 2017 Oct 10 |
4 |
| 43 |
26319559 | Hypoxia-Induced Iron Accumulation in Oligodendrocytes Mediates Apoptosis by Eliciting Endoplasmic Reticulum Stress. | 2016 Sep |
2 |
| 44 |
26629341 | The role of iron in pulmonary pathology. | 2015 |
3 |
| 45 |
24285726 | IRP2 regulates breast tumor growth. | 2014 Jan 15 |
3 |
| 46 |
24394537 | Iron transport through ferroportin is induced by intracellular ascorbate and involves IRP2 and HIF2α. | 2014 Jan 3 |
3 |
| 47 |
24778179 | HERC2 targets the iron regulator FBXL5 for degradation and modulates iron metabolism. | 2014 Jun 6 |
2 |
| 48 |
25117307 | Regulatory effect of iron regulatory protein-2 on iron metabolism in lung cancer. | 2014 Jul 25 |
1 |
| 49 |
23520538 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin promotes BHV-1 infection in mammalian cells by interfering with iron homeostasis regulation. | 2013 |
2 |
| 50 |
23891004 | Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins. | 2013 Aug 6 |
3 |