Oligonucleotides

BCL2 like 1 ; Homo sapiens







71 Article(s)
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1 29246296 Antisense Oligonucleotides Targeting Y-Box Binding Protein-1 Inhibit Tumor Angiogenesis by Downregulating Bcl-xL-VEGFR2/-Tie Axes. 2017 Dec 15 1
2 26718027 Pro-apoptotic effects of splice-switching oligonucleotides targeting Bcl-x pre-mRNA in human glioma cell lines. 2016 Feb 1
3 27579319 Modulation of Bcl-x Alternative Splicing Induces Apoptosis of Human Hepatic Stellate Cells. 2016 1
4 24637737 Reversing multidrug resistance in Caco-2 by silencing MDR1, MRP1, MRP2, and BCL-2/BCL-xL using liposomal antisense oligonucleotides. 2014 1
5 23353574 Large-scale screening identifies a novel microRNA, miR-15a-3p, which induces apoptosis in human cancer cell lines. 2013 Feb 1
6 23480956 A pH-responsive cyclodextrin-based hybrid nanosystem as a nonviral vector for gene delivery. 2013 May 1
7 17224645 Bcl2/bcl-xL inhibitor engenders apoptosis and increases chemosensitivity in mesothelioma. 2007 Feb 2
8 17697540 [Effects of STAT3 antisense oligonucleotide on proliferation and apoptosis of non-small cell lung cancer cell line A549]. 2007 Aug 1
9 18029612 Inhibition of bcl-xL expression by antisense oligonucleotides containing various bridged nucleic acids (BNAs). 2007 1
10 16374552 Cyclin D1 overexpression induces epidermal growth factor-independent resistance to apoptosis linked to BCL-2 in human A431 carcinoma. 2006 Jan 1
11 16412215 Modulation of 5' splice site selection using tailed oligonucleotides carrying splicing signals. 2006 Jan 13 1
12 16686729 Induction of apoptosis and enhancement of chemosensitivity in human prostate cancer LNCaP cells using bispecific antisense oligonucleotide targeting Bcl-2 and Bcl-xL genes. 2006 Jun 2
13 17150931 Antisense activity of 2',4'-BNA targeted to bcl-xL gene in HepG2 cell. 2006 2
14 17172421 Chemosensitization of carcinoma cells using epithelial cell adhesion molecule-targeted liposomal antisense against bcl-2/bcl-xL. 2006 Dec 1
15 15820062 [Regulatory effect of STAT5 decoy oligonucleotides on trans-activation of bcl-x gene promoter in K562 cells]. 2005 Apr 2
16 15917659 Antisense-mediated downregulation of anti-apoptotic proteins induces apoptosis and sensitizes head and neck squamous cell carcinoma cells to chemotherapy. 2005 Jul 1
17 16085054 Regulation of Bcl-2 and Bcl-xL anti-apoptotic protein expression by nuclear receptor PXR in primary cultures of human and rat hepatocytes. 2005 Aug 15 1
18 16275990 A novel antisense oligonucleotide inhibiting several antiapoptotic Bcl-2 family members induces apoptosis and enhances chemosensitivity in androgen-independent human prostate cancer PC3 cells. 2005 Nov 8
19 16299354 Chimeric peptide nucleic acid compounds modulate splicing of the bcl-x gene in vitro and in vivo. 2005 1
20 14676192 Hypoxia selection of death-resistant cells. A role for Bcl-X(L). 2004 Mar 5 1
21 14960579 Activation of intrinsic and extrinsic proapoptotic signaling pathways in interleukin-18-mediated human cardiac endothelial cell death. 2004 May 7 1
22 14985457 Enhanced oxaliplatin-induced apoptosis following antisense Bcl-xl down-regulation is p53 and Bax dependent: Genetic evidence for specificity of the antisense effect. 2004 Feb 2
23 15141012 Antisense oligonucleotides directed at the bcl-xl gene product augment chemotherapy response in mesothelioma. 2004 May 4
24 15159020 Down-regulation of protein kinase Ceta by antisense oligonucleotides sensitises A549 lung cancer cells to vincristine and paclitaxel. 2004 Jun 25 1
25 15332326 BCNU down-regulates anti-apoptotic proteins bcl-xL and Bcl-2 in association with cell death in oligodendroglioma-derived cells. 2004 Jul 1
26 15375570 Apoptotic responsiveness of PC-3 prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand: evidence for differential effects of Bcl-xL and Bcl-2 down-regulation. 2004 Oct 1
27 15379893 P2Y receptors activate neuroprotective mechanisms in astrocytic cells. 2004 Oct 1
28 15505422 Bcl-2 and CCND1/CDK4 expression levels predict the cellular effects of mTOR inhibitors in human ovarian carcinoma. 2004 Nov 1
29 15570009 Trastuzumab down-regulates Bcl-2 expression and potentiates apoptosis induction by Bcl-2/Bcl-XL bispecific antisense oligonucleotides in HER-2 gene--amplified breast cancer cells. 2004 Nov 15 1
30 15625915 A functionally improved locked nucleic acid antisense oligonucleotide inhibits Bcl-2 and Bcl-xL expression and facilitates tumor cell apoptosis. 2004 3
31 12543166 Sensitization of head and neck squamous cell carcinoma cells to Fas-mediated apoptosis by the inhibition of Bcl-X(L) expression. 2003 Feb 1
32 12558990 Down-regulation of Bcl-2 and Bcl-xL expression with bispecific antisense treatment in glioblastoma cell lines induce cell death. 2003 Jan 2
33 12800189 Induction of apoptosis and chemosensitization of mesothelioma cells by Bcl-2 and Bcl-xL antisense treatment. 2003 Aug 20 2
34 12855666 Antisense Bcl-xl down-regulation switches the response to topoisomerase I inhibition from senescence to apoptosis in colorectal cancer cells, enhancing global cytotoxicity. 2003 Jul 1
35 14520471 Bcl-x(L) antisense oligonucleotides radiosensitise colon cancer cells. 2003 Oct 6 5
36 14522969 Reprogramming alternative pre-messenger RNA splicing through the use of protein-binding antisense oligonucleotides. 2003 Dec 12 1
37 14627985 Treatment of melanoma cells with a bcl-2/bcl-xL antisense oligonucleotide induces antiangiogenic activity. 2003 Nov 20 2
38 11792421 Inhibition of Bcl-xL expression sensitizes T-cell acute lymphoblastic leukemia cells to chemotherapeutic drugs. 2002 Mar 1
39 11874491 Bcl-2 and bcl-xL antisense oligonucleotides induce apoptosis in melanoma cells of different clinical stages. 2002 Mar 4
40 11948488 Bcl-X(L) is a chemoresistance factor in human melanoma cells that can be inhibited by antisense therapy. 2002 May 1 3
41 11986224 Constitutive nuclear factor-kappaB activity preserves homeostasis of quiescent mature lymphocytes and granulocytes by controlling the expression of distinct Bcl-2 family proteins. 2002 May 15 3
42 12031489 Analysis of ribosyl-modified, mixed backbone analogs of a bcl-2/bcl-xL antisense oligonucleotide. 2002 Jun 7 5
43 12063468 Antisense therapy for malignant mesothelioma with oligonucleotides targeting the bcl-xl gene product. 2002 Jun 5
44 12070027 Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-x(L) is an essential survival protein of human myeloma cells. 2002 Jul 1 1
45 12218266 Bcl-xL antisense oligonucleotides chemosensitize human glioblastoma cells. 2002 Sep 5
46 12381725 Cellular response to an antisense-mediated shift of Bcl-x pre-mRNA splicing and antineoplastic agents. 2002 Dec 20 1
47 12393593 Overexpression of the myeloma-associated oncogene fibroblast growth factor receptor 3 confers dexamethasone resistance. 2002 Nov 15 1
48 12452453 Bcl-2/bcl-xL bispecific antisense treatment sensitizes breast carcinoma cells to doxorubicin, paclitaxel and cyclophosphamide. 2002 Nov 1
49 12570053 BcI-xL antisense treatment sensitizes Bcl-xL-overexpressing squamous cell carcinoma cells to carboplatin. 2002 Dec 4
50 11259472 Activity of a novel bcl-2/bcl-xL-bispecific antisense oligonucleotide against tumors of diverse histologic origins. 2001 Mar 21 7