Cyclic AMP

phosphodiesterase 11A ; Homo sapiens







29 Article(s)
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Pub. Year
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1 35402764 An Overview of the Heterogeneous Causes of Cushing Syndrome Resulting From Primary Macronodular Adrenal Hyperplasia (PMAH). 2022 May 1 1
2 33127481 A phosphodiesterase 11 (Pde11a) knockout mouse expressed functional but reduced Pde11a: Phenotype and impact on adrenocortical function. 2021 Jan 15 1
3 33835157 Exome sequencing revealed PDE11A as a novel candidate gene for early-onset Alzheimer's disease. 2021 May 28 2
4 32097969 Update of Genetic and Molecular Causes of Adrenocortical Hyperplasias Causing Cushing Syndrome. 2020 Aug 1
5 30941100 Phosphodiesterases and cAMP Pathway in Pituitary Diseases. 2019 2
6 29594118 The Many Faces of Primary Aldosteronism and Cushing Syndrome: A Reflection of Adrenocortical Tumor Heterogeneity. 2018 1
7 30075949 Genetics of primary macronodular adrenal hyperplasia. 2018 Jul - Aug 1
8 26724956 Active 3'-5' cyclic nucleotide phosphodiesterases are present in detergent-resistant membranes of mural granulosa cells. 2017 Apr 3
9 28956334 A Role for Phosphodiesterase 11A (PDE11A) in the Formation of Social Memories and the Stabilization of Mood. 2017 1
10 27625633 Alterations of Phosphodiesterases in Adrenocortical Tumors. 2016 6
11 25056711 Cyclic nucleotide phosphodiesterases: important signaling modulators and therapeutic targets. 2015 Jan 2
12 25578602 Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary. 2015 Mar 5 2
13 25232906 Phosphodiesterases and adrenal Cushing in mice and humans. 2014 Nov 2
14 23771924 Cyclic AMP and c-KIT signaling in familial testicular germ cell tumor predisposition. 2013 Aug 1
15 22996146 Phosphodiesterase 11A (PDE11A) gene defects in patients with acth-independent macronodular adrenal hyperplasia (AIMAH): functional variants may contribute to genetic susceptibility of bilateral adrenal tumors. 2012 Nov 8
16 21047926 Frequent phosphodiesterase 11A gene (PDE11A) defects in patients with Carney complex (CNC) caused by PRKAR1A mutations: PDE11A may contribute to adrenal and testicular tumors in CNC as a modifier of the phenotype. 2011 Jan 1
17 19429701 Abnormalities of cAMP signaling are present in adrenocortical lesions associated with ACTH-independent Cushing syndrome despite the absence of mutations in known genes. 2009 Jul 1
18 19557111 Association of PDE11A global haplotype with major depression and antidepressant drug response. 2009 1
19 19689430 Binding of cyclic nucleotides to phosphodiesterase 10A and 11A GAF domains does not stimulate catalytic activity. 2009 Oct 12 1
20 18431404 A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex. 2008 Oct 4
21 18438169 Unraveling the molecular basis of micronodular adrenal hyperplasia. 2008 Jun 2
22 17696499 N-Terminal domain of phosphodiesterase-11A4 (PDE11A4) decreases affinity of the catalytic site for substrates and tadalafil, and is involved in oligomerization. 2007 Sep 11 2
23 16767104 A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia. 2006 Jul 3
24 17036196 PRKAR1A mutations in primary pigmented nodular adrenocortical disease. 2006 1
25 15627479 Dexamethasone down-regulates cAMP-phosphodiesterase in human osteosarcoma cells. 2005 Jan 15 1
26 15995148 Expression of PDE11A in normal and malignant human tissues. 2005 Jul 1
27 11121118 Genomic organization of the human phosphodiesterase PDE11A gene. Evolutionary relatedness with other PDEs containing GAF domains. 2001 Jan 1
28 10725373 Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A. 2000 Mar 28 1
29 11050148 Cloning and characterization of two splice variants of human phosphodiesterase 11A. 2000 Nov 7 3