Title : Update of Genetic and Molecular Causes of Adrenocortical Hyperplasias Causing Cushing Syndrome.

Pub. Date : 2020 Aug

PMID : 32097969






1 Functional Relationships(s)
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1 Although mutations of the regulatory subunit R1alpha of PKA (PRKAR1A) is the main cause of familial and sporadic PPNAD, inactivation of two cAMP-binding phosphodiesterases (PDE11A and PDE8B) are associated with iMAD even if they are also found in PPNAD and PBMAH cases. Cyclic AMP phosphodiesterase 11A Homo sapiens