Mannoheptulose

glucokinase ; Homo sapiens







18 Article(s)
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1 34532767 The novel GCK variant p.Val455Leu associated with hyperinsulinism is susceptible to allosteric activation and is conducive to weight gain and the development of diabetes. 2021 Dec 1
2 26028562 Physiological characterization of the human EndoC-βH1 β-cell line. 2015 Aug 14 1
3 22210318 Brain glucose sensors play a significant role in the regulation of pancreatic glucose-stimulated insulin secretion. 2012 Feb 1
4 22305745 Additive activation of glucokinase by the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and the chemical activator LY2121260. 2012 May 1 2
5 15667334 Glucokinase and glucose homeostasis: proven concepts and new ideas. 2005 Feb 5
6 14988235 Stimulation of hepatocyte glucose metabolism by novel small molecule glucokinase activators. 2004 Mar 1
7 15202024 Dissimilar effects of D-mannoheptulose on the phosphorylation of alpha- versus beta-D-glucose by either hexokinase or glucokinase. 2004 Jul 1
8 12711325 Direct measurement of glucose gradients and mass transport within islets of Langerhans. 2003 May 2 1
9 11076949 Analysis of the cooperativity of human beta-cell glucokinase through the stimulatory effect of glucose on fructose phosphorylation. 2001 Feb 9 1
10 10677361 Investigation of the mechanism by which glucose analogues cause translocation of glucokinase in hepatocytes: evidence for two glucose binding sites. 2000 Mar 1 4
11 10679232 The role of glucose and its metabolism in the regulation of glucokinase expression in isolated human pancreatic islets. 2000 Feb 16 1
12 10868935 Study of the regulatory properties of glucokinase by site-directed mutagenesis: conversion of glucokinase to an enzyme with high affinity for glucose. 2000 Feb 1
13 9878701 Glucose and non-glucidic nutrients exert permissive effects on 2-keto acid regulation of pancreatic beta-cell function. 1999 Jan 4 1
14 9762360 The physiological role of glucokinase binding and translocation in hepatocytes. 1998 1
15 8679719 Kinetics and specificity of human B-cell glucokinase: relevance to hexose-induced insulin release. 1996 Jun 5 1
16 7614462 High Km glucose-phosphorylating (glucokinase) activities in a range of tumor cell lines and inhibition of rates of tumor growth by the specific enzyme inhibitor mannoheptulose. 1995 Aug 1 3
17 1470224 Inhibition of aconitase by alloxan and the differential modes of protection of glucose, 3-O-methylglucose, and mannoheptulose. 1992 Nov 1
18 3207996 Structural requirements of alloxan and ninhydrin for glucokinase inhibition and of glucose for protection against inhibition. 1988 Nov 1