Title : Structural requirements of alloxan and ninhydrin for glucokinase inhibition and of glucose for protection against inhibition.

Pub. Date : 1988 Nov

PMID : 3207996






1 Functional Relationships(s)
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Protein Name
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1 Only glucose derivatives with a sufficiently bulky substituent in position C-2, such as the glucokinase substrates glucose and mannose and the inhibitors mannoheptulose, glucosamine, and N-acetylglucosamine, protected glucokinase against inhibition by alloxan by binding to the active site of the enzyme. Mannoheptulose glucokinase Homo sapiens