Adenosine Triphosphate

glucokinase ; Homo sapiens







31 Article(s)
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1 32286938 Recent Developments in Medicinal Chemistry of Allosteric Activators of Human Glucokinase for Type 2 Diabetes Mellitus Therapeutics. 2020 2
2 33091480 Glucokinase in stellate ganglia cooperates with P2X3 receptor to develop cardiac sympathetic neuropathy in type 2 diabetes rats. 2020 Dec 2
3 31388064 Identification of alkaline pH optimum of human glucokinase because of ATP-mediated bias correction in outcomes of enzyme assays. 2019 Aug 6 3
4 29648519 Glutamate dehydrogenase: role in regulating metabolism and insulin release in pancreatic β-cells. 2018 Aug 1 2
5 29885360 Determinants of human glucokinase activation and implications for small molecule allosteric control. 2018 Sep 2
6 29090276 A novel mammalian glucokinase exhibiting exclusive inorganic polyphosphate dependence in the cell nucleus. 2017 Dec 4
7 26028562 Physiological characterization of the human EndoC-βH1 β-cell line. 2015 Aug 14 1
8 22107947 Homotropic allosteric regulation in monomeric mammalian glucokinase. 2012 Mar 15 1
9 22829728 Comparison and correlation of binding mode of ATP in the kinase domains of Hexokinase family. 2012 1
10 21420961 Crystal structure of E339K mutated human glucokinase reveals changes in the ATP binding site. 2011 Apr 20 1
11 22101819 The active conformation of human glucokinase is not altered by allosteric activators. 2011 Nov 2
12 19459610 Binding kinetics of glucose and allosteric activators to human glucokinase reveal multiple conformational states. 2009 Jun 16 1
13 19617908 Lys169 of human glucokinase is a determinant for glucose phosphorylation: implication for the atomic mechanism of glucokinase catalysis. 2009 Jul 20 2
14 18199594 Inhibition of glucokinase translocation by AMP-activated protein kinase is associated with phosphorylation of both GKRP and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. 2008 Mar 1
15 18298419 Permanent neonatal diabetes caused by a homozygous nonsense mutation in the glucokinase gene. 2008 Jun 2
16 17260972 A pre-steady state analysis of ligand binding to human glucokinase: evidence for a preexisting equilibrium. 2007 Feb 6 2
17 17986831 Insights in congenital hyperinsulinism. 2007 2
18 15752705 Identification and characterization of the ATP-binding site in human pancreatic glucokinase. 2005 Apr 1 3
19 14688272 Oxidative stress is a mediator of glucose toxicity in insulin-secreting pancreatic islet cell lines. 2004 Mar 26 1
20 14975750 Cloning and biochemical characterization of a novel mouse ADP-dependent glucokinase. 2004 Mar 12 2
21 11551839 Brain glucose-sensing mechanisms: ubiquitous silencing by aglycemia vs. hypothalamic neuroendocrine responses. 2001 Oct 1
22 11594461 Reduced enzymatic activity of glucokinase after affinity labeling: results from spectrophotometry and electrospray ionization mass spectrometry. 2001 May 2
23 10480597 Structural model of human glucokinase in complex with glucose and ATP: implications for the mutants that cause hypo- and hyperglycemia. 1999 Sep 2
24 9684361 Purification and characterization of a glucokinase from young tomato (Lycopersicon esculentum L. Mill.) fruit. 1998 Aug 1
25 9275185 Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase. 1997 Sep 2 1
26 8639629 Initial rate and equilibrium isotope exchange studies on the ATP-dependent activity of polyphosphate Glucokinase from Propionibacterium shermanii. 1996 May 28 2
27 7619052 Variable effects of maturity-onset-diabetes-of-youth (MODY)-associated glucokinase mutations on substrate interactions and stability of the enzyme. 1995 Jul 1 2
28 2582618 Enzymatic assay of magnesium through glucokinase activation. 1989 Nov 1
29 16666820 Characterization of Sucrolysis via the Uridine Diphosphate and Pyrophosphate-Dependent Sucrose Synthase Pathway. 1989 Jun 1
30 3663182 Kinetics of hexokinase D ('glucokinase') with inosine triphosphate as phosphate donor. Loss of kinetic co-operativity with respect to glucose. 1987 Aug 1 1
31 196677 [Liberation and reassociation of the microsomal membrane glucokinase in cat liver]. 1977 1