Lapatinib

erb-b2 receptor tyrosine kinase 3 ; Homo sapiens







59 Article(s)
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51 22709873 Gene expression changes as markers of early lapatinib response in a panel of breast cancer cell lines. 2012 Jun 18 2
52 22848366 Correlation of HER2, p95HER2 and HER3 expression and treatment outcome of lapatinib plus capecitabine in her2-positive metastatic breast cancer. 2012 2
53 21252284 Synergistic effects of foretinib with HER-targeted agents in MET and HER1- or HER2-coactivated tumor cells. 2011 Mar 1
54 21385943 Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase. 2011 Mar 22 4
55 21840482 Neuregulin-1-mediated autocrine signaling underlies sensitivity to HER2 kinase inhibitors in a subset of human cancers. 2011 Aug 16 2
56 20501798 Activated phosphoinositide 3-kinase/AKT signaling confers resistance to trastuzumab but not lapatinib. 2010 Jun 1
57 19060928 Lapatinib, a HER2 tyrosine kinase inhibitor, induces stabilization and accumulation of HER2 and potentiates trastuzumab-dependent cell cytotoxicity. 2009 Feb 12 1
58 18212337 Phase II study of predictive biomarker profiles for response targeting human epidermal growth factor receptor 2 (HER-2) in advanced inflammatory breast cancer with lapatinib monotherapy. 2008 Mar 1 1
59 15755991 Heregulin-induced activation of HER2 and HER3 increases androgen receptor transactivation and CWR-R1 human recurrent prostate cancer cell growth. 2005 Mar 1 3