pirinixic acid

prostaglandin E synthase ; Mus musculus







7 Article(s)
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1 26887049 Substrate-specific effects of pirinixic acid derivatives on ABCB1-mediated drug transport. 2016 Mar 8 1
2 25037914 Identification of pirinixic acid derivatives bearing a 2-aminothiazole moiety combines dual PPARα/γ activation and dual 5-LO/mPGES-1 inhibition. 2014 Aug 15 3
3 24171493 Aminothiazole-featured pirinixic acid derivatives as dual 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 inhibitors with improved potency and efficiency in vivo. 2013 Nov 27 1
4 21410457 A pirinixic acid derivative (LP105) inhibits murine 5-lipoxygenase activity and attenuates vascular remodelling in a murine model of aortic aneurysm. 2011 Aug 1
5 19934399 The molecular pharmacology and in vivo activity of 2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid (YS121), a dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase. 2010 Mar 1
6 21110345 Functionalization of fatty acid mimetics for solid-phase coupling and subsequent target identification. 2010 Nov 1
7 19053751 Pirinixic acid derivatives as novel dual inhibitors of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase. 2008 Dec 25 1