Title : A pirinixic acid derivative (LP105) inhibits murine 5-lipoxygenase activity and attenuates vascular remodelling in a murine model of aortic aneurysm.

Pub. Date : 2011 Aug

PMID : 21410457






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 EXPERIMENTAL APPROACH We determined the effect of LP105, a pirinixic acid derivative which acts as inhibitor of 5-LOX, COX and mPGES-1, on aortic aneurysm development in mice and on 5-LOX activity in murine monocytes. pirinixic acid prostaglandin E synthase Mus musculus