Ascorbic Acid

tet methylcytosine dioxygenase 2 ; Homo sapiens







26 Article(s)
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1 35173532 Ascorbic acid induced TET2 enzyme activation enhances cancer immunotherapy efficacy in renal cell carcinoma. 2022 2
2 35176127 TET2 Suppresses VHL Deficiency-Driven Clear Cell Renal Cell Carcinoma by Inhibiting HIF Signaling. 2022 Jun 6 2
3 35532363 The cell type specific 5hmC landscape and dynamics of healthy human hematopoiesis and TET2-mutant pre-leukemia. 2022 May 9 1
4 33804775 High-Dose Vitamin C: Preclinical Evidence for Tailoring Treatment in Cancer Patients. 2021 Mar 20 1
5 33915173 TET2 Drives 5hmc Marking of GATA6 and Epigenetically Defines Pancreatic Ductal Adenocarcinoma Transcriptional Subtypes. 2021 Aug 1
6 34497762 Ascorbate Inhibits Proliferation and Promotes Myeloid Differentiation in TP53-Mutant Leukemia. 2021 4
7 32203209 Decreased vitamin C uptake mediated by SLC2A3 promotes leukaemia progression and impedes TET2 restoration. 2020 May 2
8 32355773 Restoration of TET2 deficiency inhibits tumor growth in head neck squamous cell carcinoma. 2020 Mar 3
9 32367481 Role of Chromatin Remodeling Genes and TETs in the Development of Human Midbrain Dopaminergic Neurons. 2020 Aug 1
10 32552944 [Effect of High Dose Vitamin C on Proliferation and Apoptosis of Acute Myeloid Leukemia Cells]. 2020 Jun 1
11 32759296 Ascorbic Acid Promotes KIR Demethylation during Early NK Cell Differentiation. 2020 Sep 15 1
12 32895473 Context dependent effects of ascorbic acid treatment in TET2 mutant myeloid neoplasia. 2020 Sep 7 2
13 33184433 Tet2 at the interface between cancer and immunity. 2020 Nov 12 1
14 33264617 Ascorbic Acid Promotes Plasma Cell Differentiation through Enhancing TET2/3-Mediated DNA Demethylation. 2020 Dec 1 4
15 30836118 The expression of TET3 regulated cell proliferation in HepG2 cells. 2019 May 25 1
16 31578317 Clinical remission following ascorbate treatment in a case of acute myeloid leukemia with mutations in TET2 and WT1. 2019 Oct 2 1
17 28663574 Vitamin C-induced epigenomic remodelling in IDH1 mutant acute myeloid leukaemia. 2018 Jan 2
18 29331774 The synergy of Vitamin C with decitabine activates TET2 in leukemic cells and significantly improves overall survival in elderly patients with acute myeloid leukemia. 2018 Mar 3
19 29467326 Loss of epigenetic regulator TET2 and oncogenic KIT regulate myeloid cell transformation via PI3K pathway. 2018 Feb 22 2
20 29773648 Ten-eleven translocation 2 demethylates the MMP9 promoter, and its down-regulation in preeclampsia impairs trophoblast migration and invasion. 2018 Jun 29 1
21 28192139 Vitamin C down-regulate apo(a) expression via Tet2-dependent DNA demethylation in HepG2 cells. 2017 May 2
22 28272491 Ten-Eleven Translocation-2 (Tet2) Is Involved in Myogenic Differentiation of Skeletal Myoblast Cells in Vitro. 2017 Mar 8 1
23 28601635 Silencing HIF-1α induces TET2 expression and augments ascorbic acid induced 5-hydroxymethylation of DNA in human metastatic melanoma cells. 2017 Aug 19 2
24 28823558 Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression. 2017 Sep 7 1
25 29100007 Vitamin C: C-ing a New Way to Fight Leukemia. 2017 Nov 2 1
26 25977731 Epigenetic reprogramming of melanoma cells by vitamin C treatment. 2015 1