Title : Epigenetic reprogramming of melanoma cells by vitamin C treatment.

Pub. Date : 2015

PMID : 25977731






1 Functional Relationships(s)
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1 Treatment of vitamin C at the physiological level (0.1 mM) promoted the content of 5hmC in melanoma cell lines derived from different stages toward the level of healthy melanocytes, which was comparable to the effect of overexpressing TET2. Ascorbic Acid tet methylcytosine dioxygenase 2 Homo sapiens