Fatty Acids

sterol regulatory element binding transcription factor 1 ; Homo sapiens







149 Article(s)
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1 34942305 SETD8 stabilized by USP17 epigenetically activates SREBP1 pathway to drive lipogenesis and oncogenesis of ccRCC. 2022 Feb 28 2
2 35005107 Critical roles of FTO-mediated mRNA m6A demethylation in regulating adipogenesis and lipid metabolism: Implications in lipid metabolic disorders. 2022 Jan 1
3 35046516 PRMT5 confers lipid metabolism reprogramming, tumour growth and metastasis depending on the SIRT7-mediated desuccinylation of PRMT5 K387 in tumours. 2022 Jan 19 1
4 35634673 [Research on the mechanism of hypoxia promoting the migration of lung adenocarcinoma A549 cells]. 2022 Jan 1
5 33414447 MIEF2 reprograms lipid metabolism to drive progression of ovarian cancer through ROS/AKT/mTOR signaling pathway. 2021 Jan 5 2
6 33513366 A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density. 2021 Mar 2 1
7 33742461 Ichthyosis follicularis, atrichia and photophobia (IFAP) and hereditary mucoepithelial dysplasia: Two syndromes that share a common clinical spectrum. 2021 May 1
8 33975883 Suppression of ACADM-Mediated Fatty Acid Oxidation Promotes Hepatocellular Carcinoma via Aberrant CAV1/SREBP1 Signaling. 2021 Jul 1 3
9 34019961 E2F1 promotes proliferation and metastasis of clear cell renal cell carcinoma via activation of SREBP1-dependent fatty acid biosynthesis. 2021 Aug 28 2
10 34158007 Pyruvate carboxylase promotes thyroid cancer aggressiveness through fatty acid synthesis. 2021 Jun 22 1
11 34272396 Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer. 2021 Jul 16 4
12 34531575 SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation. 2021 Sep 1
13 34539243 The Mutual Inhibition of FoxO1 and SREBP-1c Regulated the Progression of Hepatoblastoma by Regulating Fatty Acid Metabolism. 2021 3
14 34648812 FV-429 enhances the efficacy of paclitaxel in NSCLC by reprogramming HIF-1α-modulated FattyAcid metabolism. 2021 Dec 1 1
15 34884968 Neochlorogenic Acid Attenuates Hepatic Lipid Accumulation and Inflammation via Regulating miR-34a In Vitro. 2021 Dec 6 2
16 34900747 Inhibition of SREBP-1 Activation by a Novel Small-Molecule Inhibitor Enhances the Sensitivity of Hepatocellular Carcinoma Tissue to Radiofrequency Ablation. 2021 2
17 31932581 SIK2 enhances synthesis of fatty acid and cholesterol in ovarian cancer cells and tumor growth through PI3K/Akt signaling pathway. 2020 Jan 13 2
18 32160325 Reused palm oil from frying pork or potato induced expression of cytochrome P450s and the SLCO1B1 transporter in HepG2 cells. 2020 May 2
19 32218693 ACSL1 affects Triglyceride Levels through the PPARγ Pathway. 2020 2
20 32464305 Activation of SREBP-1c alters lipogenesis and promotes tumor growth and metastasis in gastric cancer. 2020 Aug 2
21 32497488 Mutations in SREBF1, Encoding Sterol Regulatory Element Binding Transcription Factor 1, Cause Autosomal-Dominant IFAP Syndrome. 2020 Jul 2 3
22 33209199 Arachidonic acid induces ER stress and apoptosis in HT-29 human colon cancer cells. 2020 Sep 1 1
23 33232284 Loss of FBP1 promotes proliferation, migration, and invasion by regulating fatty acid metabolism in esophageal squamous cell carcinoma. 2020 Nov 21 1
24 30928092 Inhibition of fatty acid synthesis arrests colorectal neoplasm growth and metastasis: Anti-cancer therapeutical effects of natural cyclopeptide RA-XII. 2019 May 14 2
25 30954075 Influences of sterol regulatory element binding protein-1c silencing on glucose production in HepG2 cells treated with free fatty acid. 2019 Apr 6 1
26 30985894 Valine increases milk fat synthesis in mammary gland of gilts through stimulating AKT/MTOR/SREBP1 pathway†. 2019 Jul 1 2
27 31223033 Pterostilbene reverses palmitic acid mediated insulin resistance in HepG2 cells by reducing oxidative stress and triglyceride accumulation. 2019 Jul 2
28 31297058 Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells. 2019 2
29 31316083 SREBP1-dependent de novo fatty acid synthesis gene expression is elevated in malignant melanoma and represents a cellular survival trait. 2019 Jul 17 1
30 31379107 Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1. 2019 Oct 4 3
31 31395683 Leelamine Is a Novel Lipogenesis Inhibitor in Prostate Cancer Cells In Vitro and In Vivo. 2019 Oct 1
32 31511501 SREBP-1 inhibitor Betulin enhances the antitumor effect of Sorafenib on hepatocellular carcinoma via restricting cellular glycolytic activity. 2019 Sep 11 2
33 31542428 Quercetin inhibition of SREBPs and ChREBP expression results in reduced cholesterol and fatty acid synthesis in C6 glioma cells. 2019 Dec 1
34 29174379 A new pathway to eSCAPe lipotoxicity. 2018 Feb 2
35 29323924 Akt Serine/Threonine Kinase 1 Regulates de Novo Fatty Acid Synthesis through the Mammalian Target of Rapamycin/Sterol Regulatory Element Binding Protein 1 Axis in Dairy Goat Mammary Epithelial Cells. 2018 Feb 7 1
36 29449559 Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer. 2018 Feb 15 2
37 30015961 Long non‑coding RNA HR1 participates in the expression of SREBP‑1c through phosphorylation of the PDK1/AKT/FoxO1 pathway. 2018 Sep 1
38 30180878 Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer. 2018 Sep 4 3
39 30545108 Oleiferasaponin A₂, a Novel Saponin from Camellia oleifera Abel. Seeds, Inhibits Lipid Accumulation of HepG2 Cells Through Regulating Fatty Acid Metabolism. 2018 Dec 12 1
40 27492885 Genetic evidence for a role of the SREBP transcription system and lipid biosynthesis in schizophrenia and antipsychotic treatment. 2017 Jun 2
41 28027934 Histone modifications in FASN modulated by sterol regulatory element-binding protein 1c and carbohydrate responsive-element binding protein under insulin stimulation are related to NAFLD. 2017 Jan 29 2
42 28041958 SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism. 2017 Feb 7 2
43 28062356 CYP4F2 repression and a modified alpha-tocopherol (vitamin E) metabolism are two independent consequences of ethanol toxicity in human hepatocytes. 2017 Apr 1
44 28256090 Sterol regulatory element-binding protein-1c orchestrates metabolic remodeling of white adipose tissue by caloric restriction. 2017 Jun 2
45 28443075 GRIM-19 Restricts HCV Replication by Attenuating Intracellular Lipid Accumulation. 2017 2
46 28587208 Xyloketal B Attenuates Fatty Acid-Induced Lipid Accumulation via the SREBP-1c Pathway in NAFLD Models. 2017 Jun 3 1
47 28594405 Oroxylin A suppresses the development and growth of colorectal cancer through reprogram of HIF1α-modulated fatty acid metabolism. 2017 Jun 8 1
48 28604762 TIP30 regulates lipid metabolism in hepatocellular carcinoma by regulating SREBP1 through the Akt/mTOR signaling pathway. 2017 Jun 12 1
49 28827664 Integrated analysis of mRNA and miRNA expression in HeLa cells expressing low levels of Nucleolin. 2017 Aug 21 1
50 26776965 Betulin alleviated ethanol-induced alcoholic liver injury via SIRT1/AMPK signaling pathway. 2016 Mar 1