| 1 |
34979318 | BIX-01294 enhances the effect of chemotherapy on colorectal cancer by inhibiting the expression of stemness genes. | 2022 Jan 29 |
1 |
| 2 |
35354905 | Selective histone methyltransferase G9a inhibition reduces metastatic development of Ewing sarcoma through the epigenetic regulation of NEU1. | 2022 Apr |
2 |
| 3 |
35634322 | Ethanol Induces Secretion of Proinflammatory Extracellular Vesicles That Inhibit Adult Hippocampal Neurogenesis Through G9a/GLP-Epigenetic Signaling. | 2022 |
1 |
| 4 |
33148527 | Radiation-induced H3K9 methylation on E-cadherin promoter mediated by ROS/Snail axis : Role of G9a signaling during lung epithelial-mesenchymal transition. | 2021 Feb |
1 |
| 5 |
33283949 | Targeting H3K9 methyltransferase G9a and its related molecule GLP as a potential therapeutic strategy for cancer. | 2021 Mar |
1 |
| 6 |
33361537 | Oxidative stress-induced aberrant G9a activation disturbs RE-1-containing neuron-specific genes expression, leading to degeneration in human SH-SY5Y neuroblastoma cells. | 2021 Jan 1 |
4 |
| 7 |
33387131 | BIX-01294, a G9a inhibitor, suppresses cell proliferation by inhibiting autophagic flux in nasopharyngeal carcinoma cells. | 2021 Jun |
2 |
| 8 |
33442400 | EHMT2 inhibitor BIX-01294 induces endoplasmic reticulum stress mediated apoptosis and autophagy in diffuse large B-cell lymphoma cells. | 2021 |
2 |
| 9 |
33708384 | Lysine methyltransferase G9a is an important modulator of trained immunity. | 2021 |
2 |
| 10 |
34102281 | The H3K9 histone methyltransferase G9a modulates renal ischemia reperfusion injury by targeting Sirt1. | 2021 Aug 20 |
2 |
| 11 |
34633777 | EHMT2 (G9a) activation in mantle cell lymphoma and its associated DNA methylation and gene expression. | 2021 Oct 12 |
1 |
| 12 |
34876693 | BIX01294 inhibits EGFR signaling in EGFR-mutant lung adenocarcinoma cells through a BCKDHA-mediated reduction in the EGFR level. | 2021 Dec |
2 |
| 13 |
31756401 | Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening. | 2020 Jan |
1 |
| 14 |
32028644 | EHMT2 Inhibition Induces Cell Death in Human Non-Small Cell Lung Cancer by Altering the Cholesterol Biosynthesis Pathway. | 2020 Feb 3 |
2 |
| 15 |
32174799 | EHMT2/G9a Inhibits Aortic Smooth Muscle Cell Death by Suppressing Autophagy Activation. | 2020 |
1 |
| 16 |
32293500 | PERK/NRF2 and autophagy form a resistance mechanism against G9a inhibition in leukemia stem cells. | 2020 Apr 15 |
1 |
| 17 |
32684241 | Euchromatin histone methyltransferase II (EHMT2) regulates the expression of ras-related GTP binding C (RRAGC) protein. | 2020 Nov |
2 |
| 18 |
30535125 | FOXO1 degradation via G9a-mediated methylation promotes cell proliferation in colon cancer. | 2019 Feb 28 |
2 |
| 19 |
31262881 | Down-regulation of Survivin by BIX-01294 Pretreatment Overcomes Resistance of Hepatocellular Carcinoma Cells to TRAIL. | 2019 Jul |
2 |
| 20 |
31615031 | The G9a Histone Methyltransferase Inhibitor BIX-01294 Modulates Gene Expression during Plasmodium falciparum Gametocyte Development and Transmission. | 2019 Oct 14 |
1 |
| 21 |
31647887 | G9a promotes cell proliferation and suppresses autophagy in gastric cancer by directly activating mTOR. | 2019 Dec |
1 |
| 22 |
29113759 | Pharmacological and transcriptional inhibition of the G9a histone methyltransferase suppresses proliferation and modulates redox homeostasis in human microvascular endothelial cells. | 2018 Feb |
2 |
| 23 |
29337058 | EHMT2 is a metastasis regulator in breast cancer. | 2018 Feb 5 |
1 |
| 24 |
29531826 | BIX-01294 sensitizes renal cancer Caki cells to TRAIL-induced apoptosis through downregulation of survivin expression and upregulation of DR5 expression. | 2018 Dec |
1 |
| 25 |
29964331 | Inhibition of euchromatin histone-lysine N-methyltransferase 2 sensitizes breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through reactive oxygen species-mediated activating transcription factor 4-C/EBP homologous protein-death receptor 5 pathway activation. | 2018 Nov |
1 |
| 26 |
30450051 | Pre-treatment or Post-treatment of Human Glioma Cells With BIX01294, the Inhibitor of Histone Methyltransferase G9a, Sensitizes Cells to Temozolomide. | 2018 |
2 |
| 27 |
27252354 | Inhibition of G9a/GLP Complex Promotes Long-Term Potentiation and Synaptic Tagging/Capture in Hippocampal CA1 Pyramidal Neurons. | 2017 Jun 1 |
1 |
| 28 |
28104027 | [Inhibition of G9a attenuates cell proliferation via the mitochondrial apoptosis pathway in lung adenocarcinoma]. | 2017 Jan 23 |
2 |
| 29 |
28454322 | Accumulation of low-dose BIX01294 promotes metastatic potential of U251 glioblastoma cells. | 2017 Mar |
2 |
| 30 |
28791052 | Inhibition of Histone Methyltransferase, Histone Deacetylase, and β-Catenin Synergistically Enhance the Cardiac Potential of Bone Marrow Cells. | 2017 |
1 |
| 31 |
29145444 | Inhibition of the H3K9 methyltransferase G9A attenuates oncogenicity and activates the hypoxia signaling pathway. | 2017 |
2 |
| 32 |
27174920 | Inhibition of EHMT2/G9a epigenetically increases the transcription of Beclin-1 via an increase in ROS and activation of NF-κB. | 2016 Jun 28 |
3 |
| 33 |
27748874 | Mechanism of G9a inhibitor BIX‑01294 acting on U251 glioma cells. | 2016 Nov |
2 |
| 34 |
27934912 | BIX01294, an inhibitor of histone methyltransferase, induces autophagy-dependent differentiation of glioma stem-like cells. | 2016 Dec 9 |
1 |
| 35 |
25634693 | Inhibition of H3K9 methyltransferase G9a induces autophagy and apoptosis in oral squamous cell carcinoma. | 2015 Mar 27 |
3 |
| 36 |
25685062 | EHMT2 inhibitor BIX-01294 induces apoptosis through PMAIP1-USP9X-MCL1 axis in human bladder cancer cells. | 2015 |
3 |
| 37 |
25843229 | A role for KMT1c in monocyte to dendritic cell differentiation: Epigenetic regulation of monocyte differentiation. | 2015 Jun |
1 |
| 38 |
26013382 | The Histone Methyltransferase Inhibitor BIX01294 Inhibits HIF-1α Stability and Angiogenesis. | 2015 Jun |
1 |
| 39 |
26089912 | Inhibition of G9a Histone Methyltransferase Converts Bone Marrow Mesenchymal Stem Cells to Cardiac Competent Progenitors. | 2015 |
2 |
| 40 |
24810902 | Properly substituted analogues of BIX-01294 lose inhibition of G9a histone methyltransferase and gain selective anti-DNA methyltransferase 3A activity. | 2014 |
3 |
| 41 |
24833465 | Histone methyltransferase G9a and H3K9 dimethylation inhibit the self-renewal of glioma cancer stem cells. | 2014 Sep |
1 |
| 42 |
24932239 | Modulation of microRNA expression in human lung cancer cells by the G9a histone methyltransferase inhibitor BIX01294. | 2014 Jun |
1 |
| 43 |
25044750 | Development of diaminoquinazoline histone lysine methyltransferase inhibitors as potent blood-stage antimalarial compounds. | 2014 Oct |
1 |
| 44 |
25079219 | Inhibition of euchromatic histone methyltransferase 1 and 2 sensitizes chronic myeloid leukemia cells to interferon treatment. | 2014 |
1 |
| 45 |
25750706 | Identification of 2,4-diamino-6,7-dimethoxyquinoline derivatives as G9a inhibitors†Electronic supplementary information (ESI) available. See DOI: 10.1039/c4md00274a. | 2014 Dec 19 |
1 |
| 46 |
22994322 | The histone methyltransferase inhibitor BIX01294 enhances the cardiac potential of bone marrow cells. | 2013 Feb 15 |
2 |
| 47 |
23466651 | Histone-lysine methyltransferase EHMT2 is involved in proliferation, apoptosis, cell invasion, and DNA methylation of human neuroblastoma cells. | 2013 Jun |
2 |
| 48 |
24322755 | BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production. | 2013 Dec |
1 |
| 49 |
22691107 | BIX-01294 treatment blocks cell proliferation, migration and contractility in ovine foetal pulmonary arterial smooth muscle cells. | 2012 Aug |
1 |
| 50 |
22781932 | IVMBIX-01294, an inhibitor of the histone methyltransferase EHMT2, disrupts histone H3 lysine 9 (H3K9) dimethylation in the cleavage-stage porcine embryo. | 2012 |
5 |