Title : Inhibition of EHMT2/G9a epigenetically increases the transcription of Beclin-1 via an increase in ROS and activation of NF-κB.

Pub. Date : 2016 Jun 28

PMID : 27174920






3 Functional Relationships(s)
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Compound Name
Protein Name
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1 We previously reported that BIX-01294 (BIX), a small molecular inhibitor of euchromatic histone-lysine N-methyltransferase 2 (EHMT2/G9a), induces reactive oxygen species (ROS)-dependent autophagy in MCF-7 cells. BIX 01294 euchromatic histone lysine methyltransferase 2 Homo sapiens
2 We previously reported that BIX-01294 (BIX), a small molecular inhibitor of euchromatic histone-lysine N-methyltransferase 2 (EHMT2/G9a), induces reactive oxygen species (ROS)-dependent autophagy in MCF-7 cells. BIX 01294 euchromatic histone lysine methyltransferase 2 Homo sapiens
3 We previously reported that BIX-01294 (BIX), a small molecular inhibitor of euchromatic histone-lysine N-methyltransferase 2 (EHMT2/G9a), induces reactive oxygen species (ROS)-dependent autophagy in MCF-7 cells. BIX 01294 euchromatic histone lysine methyltransferase 2 Homo sapiens