Arginine

arginase, liver ; Mus musculus







67 Article(s)
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1 34780773 Preclinical investigation of Pegylated arginase 1 as a treatment for retina and brain injury. 2022 Feb 1
2 34918843 Wound healing in periodontal disease induces macrophage polarization characterized by different arginine-metabolizing enzymes. 2022 Apr 2
3 34046031 Myeloid Arginase 1 Insufficiency Exacerbates Amyloid-β Associated Neurodegenerative Pathways and Glial Signatures in a Mouse Model of Alzheimer's Disease: A Targeted Transcriptome Analysis. 2021 2
4 34359992 Cytokine-Mediated Regulation of ARG1 in Macrophages and Its Impact on the Control of Salmonella enterica Serovar Typhimurium Infection. 2021 Jul 19 1
5 34518197 Arginase 1-Based Immune Modulatory Vaccines Induce Anticancer Immunity and Synergize with Anti-PD-1 Checkpoint Blockade. 2021 Nov 2
6 34520398 Breast cancer-derived GM-CSF regulates arginase 1 in myeloid cells to promote an immunosuppressive microenvironment. 2021 Oct 15 2
7 34607466 Metabolomic Analysis of Diverse Mice Reveals Hepatic Arginase-1 as Source of Plasma Arginase in Plasmodium chabaudi Infection. 2021 Oct 26 2
8 32426941 Supplementation of l-arginine boosts the therapeutic efficacy of anticancer chemoimmunotherapy. 2020 Jul 1
9 32721946 Arginase impedes the resolution of colitis by altering the microbiome and metabolome. 2020 Nov 2 5
10 33092030 Accumulation of 8-hydroxydeoxyguanosine, L-arginine and Glucose Metabolites by Liver Tumor Cells Are the Important Characteristic Features of Metabolic Syndrome and Non-Alcoholic Steatohepatitis-Associated Hepatocarcinogenesis. 2020 Oct 20 1
11 30665936 Resolution of Cutaneous Leishmaniasis and Persistence of Leishmania major in the Absence of Arginase 1. 2019 Mar 1 1
12 30728077 Suppression of Myeloid Cell Arginase Activity leads to Therapeutic Response in a NSCLC Mouse Model by Activating Anti-Tumor Immunity. 2019 Feb 6 2
13 29098611 Early obesity leads to increases in hepatic arginase I and related systemic changes in nitric oxide and L-arginine metabolism in mice. 2018 Feb 1
14 29450408 Effect of Arginase-1 Inhibition on the Incidence of Autoimmune Diabetes in NOD Mice. 2018 Jan 2
15 29792217 Hypoargininemia exacerbates airway hyperresponsiveness in a mouse model of asthma. 2018 May 23 1
16 29890043 Deletion of endothelial arginase 1 does not improve vasomotor function in diabetic mice. 2018 Jun 1
17 30042193 Interactions between Macrophages and Cyst-Lining Epithelial Cells Promote Kidney Cyst Growth in Pkd1-Deficient Mice. 2018 Sep 1
18 30206632 The inhibitory role of intracellular free zinc in the regulation of Arg-1 expression in interleukin-4-induced activation of M2 microglia. 2018 Oct 17 1
19 30254218 Arginase 1 promotes retinal neurovascular protection from ischemia through suppression of macrophage inflammatory responses. 2018 Sep 25 2
20 30288668 L-Norvaline Reverses Cognitive Decline and Synaptic Loss in a Murine Model of Alzheimer's Disease. 2018 Oct 1
21 30429607 Autophagy maintains tumour growth through circulating arginine. 2018 Nov 2
22 27998825 Hematopoietic arginase 1 deficiency results in decreased leukocytosis and increased foam cell formation but does not affect atherosclerosis. 2017 Jan 2
23 29183288 Arginase 1 deletion in myeloid cells affects the inflammatory response in allergic asthma, but not lung mechanics, in female mice. 2017 Nov 28 1
24 27043409 Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation. 2016 Jun 1
25 27761413 Liver-specific knockout of arginase-1 leads to a profound phenotype similar to inducible whole body arginase-1 deficiency. 2016 Dec 2
26 25938595 Strategies to rescue the consequences of inducible arginase-1 deficiency in mice. 2015 1
27 26467175 Arginase-1 deficiency. 2015 Dec 1
28 26491198 Expression of Cationic Amino Acid Transporter 2 Is Required for Myeloid-Derived Suppressor Cell-Mediated Control of T Cell Immunity. 2015 Dec 1 2
29 26538654 Sustained Arginase 1 Expression Modulates Pathological Tau Deposits in a Mouse Model of Tauopathy. 2015 Nov 4 2
30 26576438 Charge-Based Inhibitors of Amylin Fibrillization and Toxicity. 2015 1
31 23470573 The central role of arginine catabolism in T-cell dysfunction and increased susceptibility to infection after physical injury. 2014 Jan 1
32 24465919 Arginase-1 deficiency regulates arginine concentrations and NOS2-mediated NO production during endotoxemia. 2014 2
33 25009204 Repression of arginase-2 expression in dendritic cells by microRNA-155 is critical for promoting T cell proliferation. 2014 Aug 15 1
34 25033204 Endothelial arginine resynthesis contributes to the maintenance of vasomotor function in male diabetic mice. 2014 1
35 25201986 Macrophage arginase-1 controls bacterial growth and pathology in hypoxic tuberculosis granulomas. 2014 Sep 23 1
36 23179835 Generation and characterization of murine alternatively activated macrophages. 2013 1
37 23248265 The key role of IL-6-arginase cascade for inducing dendritic cell-dependent CD4(+) T cell dysfunction in tumor-bearing mice. 2013 Jan 15 1
38 23785515 Hepatic adaptation compensates inactivation of intestinal arginine biosynthesis in suckling mice. 2013 1
39 23831616 Ablation of Arg1 in hematopoietic cells improves respiratory function of lung parenchyma, but not that of larger airways or inflammation in asthmatic mice. 2013 Sep 2
40 24400007 l-Citrulline Protects from Kidney Damage in Type 1 Diabetic Mice. 2013 1
41 22348173 Recombinant human arginase toxicity in mice is reduced by citrulline supplementation. 2012 Feb 1
42 22361732 L-arginine uptake by cationic amino acid transporter 2 is essential for colonic epithelial cell restitution. 2012 May 1 1
43 22865229 Deacetylation of C/EBPβ is required for IL-4-induced arginase-1 expression in murine macrophages. 2012 Nov 1
44 22885179 L-glutamine is a key parameter in the immunosuppression phenomenon. 2012 Sep 7 2
45 21585399 Arginase-1-expressing macrophages are dispensable for resistance to infection with the gastrointestinal helminth Trichuris muris. 2011 Jul 1
46 21775527 Selenium levels affect the IL-4-induced expression of alternative activation markers in murine macrophages. 2011 Sep 2
47 21804013 Myeloid-derived suppressor cells infiltrate the heart in acute Trypanosoma cruzi infection. 2011 Sep 1 2
48 19800904 Arginase inhibition in airways from normal and nitric oxide synthase 2-knockout mice exposed to ovalbumin. 2010 Jan 1 1
49 20382750 Direct inhibition of arginase attenuated airway allergic reactions and inflammation in a Dermatophagoides farinae-induced NC/Nga mouse model. 2010 Jul 1
50 20463604 Alternatively activated macrophage possess antitumor cytotoxicity that is induced by IL-4 and mediated by arginase-1. 2010 Jun 1