Pub. Date : 2021 Oct 26
PMID : 34607466
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In our malarial mice, liver damage, which releases hepatic arginase-1 (Arg1) into circulation, correlated with plasma arginine depletion. | Arginine | arginase, liver | Mus musculus |
2 | Specifically, we showed that liver damage in P. chabaudi-infected mice releases hepatic arginase-1 into circulation, where it may deplete plasma arginine, a candidate malaria therapeutic that mitigates vascular stress. | Arginine | arginase, liver | Mus musculus |