Title : Diphenhydramine increases the therapeutic window for platinum drugs by simultaneously sensitizing tumor cells and protecting normal cells.

Pub. Date : 2020 Apr

PMID : 32037720






1 Functional Relationships(s)
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Protein Name
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1 Mechanistically, DIPH diminished transport capacity of cisplatin efflux pumps MRP2, MRP3 and MRP5 particularly in its C2+C6 bi-methylated form. Cisplatin ATP binding cassette subfamily C member 2 Homo sapiens