Serine

signal transducer and activator of transcription 1 ; Homo sapiens







147 Article(s)
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101 12883649 Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation. 2003 Sep 1
102 14517348 Inhibition of interferon gamma signaling by the short chain fatty acid butyrate. 2003 Sep 1
103 14670293 Serine phosphorylation: arming Stat1 against infection. 2003 Dec 3
104 11777927 Activation of signal transducer and activator of transcription 1 (STAT1) is not sufficient for the induction of STAT1-dependent genes in endothelial cells. Comparison of interferon-gamma and oncostatin M. 2002 Mar 8 1
105 11875080 Regulation of erythropoietin-induced STAT serine phosphorylation by distinct mitogen-activated protein kinases. 2002 May 10 2
106 11884587 Stat1-dependent, p53-independent expression of p21(waf1) modulates oxysterol-induced apoptosis. 2002 Apr 1
107 11886239 Dephosphorylation failure of tyrosine-phosphorylated STAT1 in IFN-stimulated Sendai virus C protein-expressing cells. 2002 Feb 15 1
108 11972023 Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-gamma. 2002 Apr 30 1
109 12018856 Increased serine phosphorylation and activation of STAT1 by oncogenic Ras transfection. 2002 Apr 30 4
110 12051728 Involvement of IL-1beta and IL-10 in IFN-alpha-mediated antiviral gene induction in human hepatoma cells. 2002 Jun 7 1
111 12068083 Interferon-beta activates multiple signaling cascades in primary human microglia. 2002 Jun 1
112 12161037 Low expression of interferon-stimulated genes in active multiple sclerosis is linked to subnormal phosphorylation of STAT1. 2002 Aug 1
113 12171910 Arginine methylation of STAT1 regulates its dephosphorylation by T cell protein tyrosine phosphatase. 2002 Sep 27 1
114 12232043 p38 MAPK enhances STAT1-dependent transcription independently of Ser-727 phosphorylation. 2002 Oct 1 3
115 12232802 The C-terminal activation domain of the STAT-1 transcription factor is necessary and sufficient for stress-induced apoptosis. 2002 Oct 1
116 12270932 SHP-2 is a dual-specificity phosphatase involved in Stat1 dephosphorylation at both tyrosine and serine residues in nuclei. 2002 Dec 6 4
117 11309387 Induction of apoptosis and Fas receptor/Fas ligand expression by ischemia/reperfusion in cardiac myocytes requires serine 727 of the STAT-1 transcription factor but not tyrosine 701. 2001 Jul 27 6
118 11438544 Roles of phosphatidylinositol 3-kinase in interferon-gamma-dependent phosphorylation of STAT1 on serine 727 and activation of gene expression. 2001 Sep 7 8
119 10637471 Serine/threonine phosphorylation in cytokine signal transduction. 2000 Jan 2
120 10645003 Inhibition of collagenase-3 (MMP-13) expression in transformed human keratinocytes by interferon-gamma is associated with activation of extracellular signal-regulated kinase-1,2 and STAT1. 2000 Jan 13 1
121 10748192 Signaling via the T cell antigen receptor induces phosphorylation of Stat1 on serine 727. 2000 Jun 2 3
122 10777558 Distinct mechanisms of STAT phosphorylation via the interferon-alpha/beta receptor. Selective inhibition of STAT3 and STAT5 by piceatannol. 2000 Apr 28 2
123 10792030 Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes. 2000 May 9 5
124 10878008 The Rac1/p38 mitogen-activated protein kinase pathway is required for interferon alpha-dependent transcriptional activation but not serine phosphorylation of Stat proteins. 2000 Sep 8 2
125 10918594 IFN-beta induces serine phosphorylation of Stat-1 in Ewing's sarcoma cells and mediates apoptosis via induction of IRF-1 and activation of caspase-7. 2000 Jul 13 2
126 10940874 Antigen receptor signal transduction: activating and inhibitory antigen receptors regulate STAT1 serine phosphorylation. 2000 Jul 7
127 10201984 The functional synergy between IL-12 and IL-2 involves p38 mitogen-activated protein kinase and is associated with the augmentation of STAT serine phosphorylation. 1999 Apr 15 1
128 10329948 Thyroid hormone induces activation of mitogen-activated protein kinase in cultured cells. 1999 May 1
129 10349599 Activation of STAT1 alpha by phosphatase inhibitor vanadate in glomerular mesangial cells: involvement of tyrosine and serine phosphorylation. 1999 Sep 2
130 10523304 p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons. 1999 Oct 15 2
131 10542198 Rapid STAT phosphorylation via the B cell receptor. Modulatory role of CD19. 1999 Nov 5 2
132 9633897 Differential constitutive activation between STAT-related proteins and MAP kinase in primary acute myelogenous leukaemia. 1998 Jun 1
133 9649436 Stat1 combines signals derived from IFN-gamma and LPS receptors during macrophage activation. 1998 Jul 1 1
134 9668040 Activation of Raf-1 by interferon gamma and oncostatin M requires expression of the Stat1 transcription factor. 1998 Jul 24 2
135 9153303 Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3. 1997 Jun 1 3
136 9182578 Two discrete regions of interleukin-2 (IL2) receptor beta independently mediate IL2 activation of a PD98059/rapamycin/wortmannin-insensitive Stat5a/b serine kinase. 1997 Jun 13 1
137 9343414 STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation. 1997 Nov 3
138 9343425 Stat1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase. 1997 Nov 6
139 9353323 Targeted inhibition of interferon-gamma-dependent intercellular adhesion molecule-1 (ICAM-1) expression using dominant-negative Stat1. 1997 Nov 7 1
140 9399961 B lymphocytes from patients with chronic lymphocytic leukemia contain signal transducer and activator of transcription (STAT) 1 and STAT3 constitutively phosphorylated on serine residues. 1997 Dec 15 11
141 8523587 The antiviral state induced by alpha interferon and gamma interferon requires transcriptionally active Stat1 protein. 1996 Jan 1
142 8647800 Insulin stimulates the serine phosphorylation of the signal transducer and activator of transcription (STAT3) isoform. 1996 May 24 1
143 8683106 Differential utilization of Janus kinase-signal transducer activator of transcription signaling pathways in the stimulation of human natural killer cells by IL-2, IL-12, and IFN-alpha. 1996 Jul 1 1
144 8943379 Activation of STAT4 by IL-12 and IFN-alpha: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation. 1996 Dec 1 1
145 7543024 Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. 1995 Jul 28 2
146 7701321 Requirement of serine phosphorylation for formation of STAT-promoter complexes. 1995 Mar 31 1
147 7791765 Differentiation-regulated serine phosphorylation of STAT1 promotes GAF activation in macrophages. 1995 Jul 2