zaprinast

phosphodiesterase 5A ; Homo sapiens







25 Article(s)
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1 24550991 Stimulation of neural stem cell proliferation by inhibition of phosphodiesterase 5. 2014 1
2 24977346 Cross regulation between cGMP-dependent protein kinase and Akt in vasodilatation of porcine pulmonary artery. 2014 Nov 1
3 23986226 Synergistic effects of prostacyclin analogs and phosphodiesterase inhibitors on cyclic adenosine 3',5' monophosphate accumulation and adenosine 3'5' triphosphate release from human erythrocytes. 2013 Sep 1
4 21791937 Effect of a phosphodiesterase 5 inhibitor on pulmonary and cerebral arteries of newborn piglets with chronic hypoxia-induced pulmonary hypertension. 2012 2
5 22028410 Testosterone regulates smooth muscle contractile pathways in the rat prostate: emphasis on PDE5 signaling. 2012 Jan 15 2
6 23086989 Melatonin inhibits nitric oxide signaling by increasing PDE5 phosphorylation in coronary arteries. 2012 Dec 15 1
7 21717503 Developmental and spinal cord injury-induced changes in nitric oxide-mediated inhibition in rat urinary bladder. 2011 Nov 1
8 18282775 Phosphodiesterase 4 inhibitors delay human eosinophil and neutrophil apoptosis in the absence and presence of salbutamol. 2008 1
9 15567064 The effect of Sildenafil on human platelet secretory function is controlled by a complex interplay between phosphodiesterases 2, 3 and 5. 2005 Mar 1
10 15792963 Cyclic GMP-specific phosphodiesterase 5 regulates growth and apoptosis in pulmonary endothelial cells. 2005 Aug 1
11 16157016 Phosphodiesterase 5 inhibitor, zaprinast, selectively increases cerebral blood flow in the ischemic penumbra in the rat brain. 2005 Sep 1
12 14722776 Nitric oxide inhibits arginine-vasotocin-induced increase of water osmotic permeability in frog urinary bladder. 2004 May 1
13 15295092 Postnatal maturation of phosphodiesterase 5 (PDE5) in piglet pulmonary arteries: activity, expression, effects of PDE5 inhibitors, and role of the nitric oxide/cyclic GMP pathway. 2004 Oct 1
14 15571296 Cyclic nucleotides and neuroblastoma differentiation. 2004 Oct 1
15 14602552 Phosphorylation of the vasodilator-stimulated phosphoprotein (VASP) by the anti-platelet drug, cilostazol, in platelets. 2003 Sep 1
16 11805217 Immunopharmacological potential of selective phosphodiesterase inhibition. I. Differential regulation of lipopolysaccharide-mediated proinflammatory cytokine (interleukin-6 and tumor necrosis factor-alpha) biosynthesis in alveolar epithelial cells. 2002 Feb 1
17 11969359 Modulation of TNF and GM-CSF release from dispersed human nasal polyp cells and human whole blood by inhibitors of different PDE isoenzymes and glucocorticoids. 2002 1
18 11388700 Characterization of human, dog and rabbit corpus cavernosum type 5 phosphodiesterases. 2001 Mar 16 1
19 10679826 Expression and regulation of the cGMP-binding, cGMP-specific phosphodiesterase (PDE5) in human colonic epithelial cells: role in the induction of cellular refractoriness to the heat-stable enterotoxin peptide. 2000 Feb 1
20 9922221 Identification and function of cyclic nucleotide phosphodiesterase isoenzymes in airway epithelial cells. 1999 Feb 1
21 10385692 Inhibition of cyclic GMP-binding cyclic GMP-specific phosphodiesterase (Type 5) by sildenafil and related compounds. 1999 Jul 3
22 9497379 Potential roles of conserved amino acids in the catalytic domain of the cGMP-binding cGMP-specific phosphodiesterase. 1998 Mar 13 1
23 9559913 Effect of PDE4 inhibitors on zymosan-induced IL-8 release from human neutrophils: synergism with prostanoids and salbutamol. 1998 Mar 1
24 9714779 Isolation and characterization of cDNAs encoding PDE5A, a human cGMP-binding, cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase. 1998 Aug 17 1
25 9723958 Effect of atrial natriuretic peptide and cyclic GMP phosphodiesterase inhibition on collagen synthesis by adult cardiac fibroblasts. 1998 Aug 1