Title : Phosphodiesterase 5 inhibitor, zaprinast, selectively increases cerebral blood flow in the ischemic penumbra in the rat brain.

Pub. Date : 2005 Sep

PMID : 16157016






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1 CONCLUSIONS: The PDE5 inhibitor zaprinast may selectively increase CBF in the ischemic brain via increased cGMP levels, thus providing a new strategy against acute cerebral infarction. zaprinast phosphodiesterase 5A Homo sapiens