1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine

BCL2-associated X protein ; Mus musculus







33 Article(s)
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1 33925146 The Neuroprotective Effects of GPR4 Inhibition through the Attenuation of Caspase Mediated Apoptotic Cell Death in an MPTP Induced Mouse Model of Parkinson's Disease. 2021 Apr 28 1
2 32333598 A Mouse Model of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Induced Parkinson Disease Shows that 2-Aminoquinoline Targets JNK Phosphorylation. 2020 Apr 25 1
3 32386222 A-Type Cinnamon Procyanidin Oligomers Protect Against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Neurotoxicity in Mice Through Inhibiting the P38 Mitogen-Activated Protein Kinase/P53/BCL-2 Associated X Protein Signaling Pathway. 2020 Jul 1 1
4 32495646 Effects of Environmental Enrichment on Neurotrophins in an MPTP-Induced Parkinson's Disease Animal Model: A Randomized Trial. 2020 Oct 2
5 31175966 G protein-coupled estrogen receptor is involved in the neuroprotective effect of IGF-1 against MPTP/MPP+-induced dopaminergic neuronal injury. 2019 Sep 1
6 31690718 Ablation of RIP3 protects from dopaminergic neurodegeneration in experimental Parkinson's disease. 2019 Nov 5 1
7 29264673 Neuroprotective effects of the gliopeptide ODN in an in vivo model of Parkinson's disease. 2018 Jun 1
8 29588573 Vitexin protects dopaminergic neurons in MPTP-induced Parkinson's disease through PI3K/Akt signaling pathway. 2018 1
9 28190476 Neuroprotective properties of icariin in MPTP-induced mouse model of Parkinson's disease: Involvement of PI3K/Akt and MEK/ERK signaling pathways. 2017 Feb 15 1
10 25730317 Lutein protects dopaminergic neurons against MPTP-induced apoptotic death and motor dysfunction by ameliorating mitochondrial disruption and oxidative stress. 2016 Jul 1
11 25976060 MiR-124 Regulates Apoptosis and Autophagy Process in MPTP Model of Parkinson's Disease by Targeting to Bim. 2016 Mar 1
12 26484597 Structure-activity relationship of sulfated hetero/galactofucan polysaccharides on dopaminergic neuron. 2016 Jan 1
13 27017962 Mitochondrial ferritin suppresses MPTP-induced cell damage by regulating iron metabolism and attenuating oxidative stress. 2016 Jul 1 1
14 27317935 Dopaminergic neuron-specific deletion of p53 gene is neuroprotective in an experimental Parkinson's disease model. 2016 Sep 6
15 27619562 Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson's disease model induced by MPTP. 2016 Sep 13 1
16 25645943 Differential regulation of caspase-2 in MPP⁺-induced apoptosis in primary cortical neurons. 2015 Mar 1 2
17 25857436 Ferulic acid pretreatment mitigates MPTP-induced motor impairment and histopathological alterations in C57BL/6 mice. 2015 1
18 24686337 BAX channel activity mediates lysosomal disruption linked to Parkinson disease. 2014 May 1
19 24995576 CNB-001, a novel pyrazole derivative mitigates motor impairments associated with neurodegeneration via suppression of neuroinflammatory and apoptotic response in experimental Parkinson's disease mice. 2014 Sep 5 1
20 23877198 Selegiline rescues gait deficits and the loss of dopaminergic neurons in a subacute MPTP mouse model of Parkinson's disease. 2013 Oct 1
21 24095822 Mangiferin attenuates MPTP induced dopaminergic neurodegeneration and improves motor impairment, redox balance and Bcl-2/Bax expression in experimental Parkinson's disease mice. 2013 Nov 25 1
22 24262283 Asiaticoside, a trisaccaride triterpene induces biochemical and molecular variations in brain of mice with parkinsonism. 2013 Nov 21 1
23 19765187 Neuroprotective effect of L-dopa on dopaminergic neurons is comparable to pramipexol in MPTP-treated animal model of Parkinson's disease: a direct comparison study. 2009 Nov 1
24 18675323 Distinct mechanisms of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine resistance revealed by transcriptome mapping in mouse striatum. 2008 Sep 9 1
25 17076657 Recombinant human granulocyte colony-stimulating factor protects against MPTP-induced dopaminergic cell death in mice by altering Bcl-2/Bax expression levels. 2006 Nov 2
26 15111020 Prevention of MPTP (N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) dopaminergic neurotoxicity in mice by chronic lithium: involvements of Bcl-2 and Bax. 2004 Jun 1
27 32585786 Prevention of MPTP (N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) dopaminergic neurotoxicity in mice by chronic lithium: involvements of Bcl-2 and Bax. 2004 Jun 1
28 12718432 The retina as a novel in vivo model for studying the role of molecules of the Bcl-2 family in relation to MPTP neurotoxicity. 2003 Jun 1
29 12200191 Apoptotic molecules and MPTP-induced cell death. 2002 Sep-Oct 1
30 12402257 p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism. 2002 Nov 1
31 11226327 Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. 2001 Feb 27 5
32 11698144 Sequential up-regulation of the c-fos, c-jun and bax genes in the cortex, striatum and cerebellum induced by a single injection of a low dose of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in C57BL/6 mice. 2001 Nov 13 4
33 8929984 Increase in bax expression in substantia nigra following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment of mice. 1996 Feb 2 4