| 1 |
33787344 | Gab1 in livers with persistent hepatocyte apoptosis has an antiapoptotic effect and reduces chronic liver injury, fibrosis, and tumorigenesis. | 2021 Jun 1 |
2 |
| 2 |
34659562 | Metformin exerts a synergistic effect with venetoclax by downregulating Mcl-1 protein in acute myeloid leukemia. | 2021 |
1 |
| 3 |
30017199 | ABT-199-mediated inhibition of Bcl-2 as a potential therapeutic strategy for nasopharyngeal carcinoma. | 2018 Sep 10 |
1 |
| 4 |
28319809 | ABT-737 Synergizes with Cisplatin Bypassing Aberration of Apoptotic Pathway in Non-small Cell Lung Cancer. | 2017 Apr |
1 |
| 5 |
28533436 | Metformin Synergizes with BCL-XL/BCL-2 Inhibitor ABT-263 to Induce Apoptosis Specifically in p53-Defective Cancer Cells. | 2017 Sep |
2 |
| 6 |
29237758 | Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis. | 2017 Dec 13 |
1 |
| 7 |
27560714 | MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL. | 2016 Aug 25 |
2 |
| 8 |
25862283 | Bcl-xL stimulates Bax relocation to mitochondria and primes cells to ABT-737. | 2015 Jul |
3 |
| 9 |
25880088 | BCL-2 is dispensable for thrombopoiesis and platelet survival. | 2015 Apr 16 |
1 |
| 10 |
26038117 | Activation of the Mitochondrial Apoptotic Pathway Produces Reactive Oxygen Species and Oxidative Damage in Hepatocytes That Contribute to Liver Tumorigenesis. | 2015 Aug |
1 |
| 11 |
24632563 | Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways. | 2014 Mar 17 |
1 |
| 12 |
25023286 | Bcl-xL protein protects from C/EBP homologous protein (CHOP)-dependent apoptosis during plasma cell differentiation. | 2014 Aug 22 |
1 |
| 13 |
25208888 | A Bim-targeting strategy overcomes adaptive bortezomib resistance in myeloma through a novel link between autophagy and apoptosis. | 2014 Oct 23 |
1 |
| 14 |
25368242 | BH3 mimetics inhibit growth of chondrosarcoma--a novel targeted-therapy for candidate models. | 2014 Nov |
2 |
| 15 |
22814621 | Prophylactic treatment with the BH3 mimetic ABT-737 impedes Myc-driven lymphomagenesis in mice. | 2013 Jan |
1 |
| 16 |
23341542 | ABT-199, a new Bcl-2-specific BH3 mimetic, has in vivo efficacy against aggressive Myc-driven mouse lymphomas without provoking thrombocytopenia. | 2013 Mar 21 |
2 |
| 17 |
23986435 | The Bcl-2 homology domain 3 (BH3)-only proteins Bim and bid are functionally active and restrained by anti-apoptotic Bcl-2 family proteins in healthy liver. | 2013 Oct 18 |
1 |
| 18 |
24227720 | Tonic activation of Bax primes neural progenitors for rapid apoptosis through a mechanism preserved in medulloblastoma. | 2013 Nov 13 |
1 |
| 19 |
21768359 | Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737. | 2012 Feb 21 |
1 |
| 20 |
21997189 | Pharmacological blockade of Bcl-2, Bcl-x(L) and Bcl-w by the BH3 mimetic ABT-737 has only minor impact on tumour development in p53-deficient mice. | 2012 Apr |
1 |
| 21 |
22510411 | A defect in cell death of macrophages is a conserved feature of nonobese diabetic mouse. | 2012 Apr 27 |
1 |
| 22 |
22790873 | Mcl-1 and Bcl-xL regulate Bak/Bax-dependent apoptosis of the megakaryocytic lineage at multistages. | 2012 Nov |
1 |
| 23 |
21719460 | Evaluation of the Bcl-2 family antagonist ABT-737 in collagen-induced arthritis. | 2011 Oct |
1 |
| 24 |
20535152 | Effective targeting of STAT5-mediated survival in myeloproliferative neoplasms using ABT-737 combined with rapamycin. | 2010 Aug |
1 |
| 25 |
18841882 | Discovery of an orally bioavailable small molecule inhibitor of prosurvival B-cell lymphoma 2 proteins. | 2008 Nov 13 |
1 |
| 26 |
19004807 | In vivo efficacy of the Bcl-2 antagonist ABT-737 against aggressive Myc-driven lymphomas. | 2008 Nov 18 |
1 |
| 27 |
17508927 | Small molecule inhibition of the Bcl-X(L)-BH3 protein-protein interaction: proof-of-concept of an in vivo chemopotentiator ABT-737. | 2007 |
1 |