Heparin

microtubule associated protein tau ; Homo sapiens







55 Article(s)
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1 35016968 Ubiquitination of Alzheimer's-related tau protein affects liquid-liquid phase separation in a site- and cofactor-dependent manner. 2022 Mar 15 1
2 35457009 Alzheimer's Disease and Tau Self-Assembly: In the Search of the Missing Link. 2022 Apr 10 1
3 35577786 Hyperphosphorylated tau self-assembles into amorphous aggregates eliciting TLR4-dependent responses. 2022 May 16 1
4 33579328 Baicalein inhibits heparin-induced Tau aggregation by initializing non-toxic Tau oligomer formation. 2021 Feb 12 2
5 33789211 SARS-CoV-2 spike protein interactions with amyloidogenic proteins: Potential clues to neurodegeneration. 2021 May 21 1
6 33826208 Direct Observation of the Self-Aggregation of R3R4 Bi-repeat of Tau Protein. 2021 Jun 15 3
7 33829789 Alginate-Derived Mannuronate Oligosaccharide Attenuates Tauopathy through Enhancing Autophagy. 2021 Apr 21 2
8 33983722 Inclusion of the C-Terminal Domain in the β-Sheet Core of Heparin-Fibrillized Three-Repeat Tau Protein Revealed by Solid-State Nuclear Magnetic Resonance Spectroscopy. 2021 May 26 2
9 34056268 Amyloid-β-Derived Peptidomimetics Inhibits Tau Aggregation. 2021 May 4 1
10 34193922 Biophysical properties of a tau seed. 2021 Jun 30 1
11 34381596 Conformational fingerprinting of tau variants and strains by Raman spectroscopy. 2021 1
12 34494046 Heparin remodels the microtubule-binding repeat R3 of Tau protein towards fibril-prone conformations. 2021 Sep 22 6
13 34718129 To target Tau pathologies, we must embrace and reconstruct their complexities. 2021 Dec 5
14 34778381 The Disease Associated Tau35 Fragment has an Increased Propensity to Aggregate Compared to Full-Length Tau. 2021 1
15 34783530 Contrasting Effects of Ferric and Ferrous Ions on Oligomerization and Droplet Formation of Tau: Implications in Tauopathies and Neurodegeneration. 2021 Dec 1 1
16 32681841 Paired Helical Filament-Forming Region of Tau (297-391) Influences Endogenous Tau Protein and Accumulates in Acidic Compartments in Human Neuronal Cells. 2020 Aug 7 1
17 33005889 Dextran sulphate-induced tau assemblies cause endogenous tau aggregation and propagation in wild-type mice. 2020 1
18 33317395 Role of cysteines in accelerating Tau filament formation. 2020 Dec 15 1
19 30720432 Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases. 2019 Feb 5 2
20 30840313 Neuronal apolipoprotein E4 increases cell death and phosphorylated tau release in alzheimer disease. 2019 May 1
21 31358628 In vitro 0N4R tau fibrils contain a monomorphic β-sheet core enclosed by dynamically heterogeneous fuzzy coat segments. 2019 Aug 13 2
22 29664486 Heparin-induced tau filaments are structurally heterogeneous and differ from Alzheimer's disease filaments. 2018 May 1 2
23 29734651 Acetylation Disfavors Tau Phase Separation. 2018 May 4 1
24 29953200 Oligomer Diversity during the Aggregation of the Repeat Region of Tau. 2018 Dec 19 1
25 30081240 Conformational heterogeneity of tau: Implication on intrinsic disorder, acid stability and fibrillation in Alzheimer's disease. 2018 Oct 1
26 27601475 Modification of Tau by 8-Nitroguanosine 3',5'-Cyclic Monophosphate (8-Nitro-cGMP): EFFECTS OF NITRIC OXIDE-LINKED CHEMICAL MODIFICATION ON TAU AGGREGATION. 2016 Oct 21 2
27 26126828 Distinct Therapeutic Mechanisms of Tau Antibodies: Promoting Microglial Clearance Versus Blocking Neuronal Uptake. 2015 Aug 28 1
28 26374846 The twenty-four KDa C-terminal tau fragment increases with aging in tauopathy mice: implications of prion-like properties. 2015 Nov 15 1
29 24444746 O-GlcNAc modification of tau directly inhibits its aggregation without perturbing the conformational properties of tau monomers. 2014 Apr 17 1
30 25153692 Amplification of Tau fibrils from minute quantities of seeds. 2014 Sep 16 2
31 25284680 Resonance Raman spectroscopic measurements delineate the structural changes that occur during tau fibril formation. 2014 Oct 21 2
32 24033133 Conformational features of tau fibrils from Alzheimer's disease brain are faithfully propagated by unmodified recombinant protein. 2013 Oct 8 5
33 24163620 Investigation on the aggregation behaviors and filament morphology of tau protein by a simple 90° angle light-scattering assay. 2013 1
34 22083130 Cooperative folding of tau peptide by coordination of group IIB metal cations during heparin-induced aggregation. 2012 Apr 1
35 22232002 Molecules of the quinoline family block tau self-aggregation: implications toward a therapeutic approach for Alzheimer's disease. 2012 2
36 22998648 Identification of an aggregation-prone structure of tau. 2012 Oct 10 1
37 20110603 Selective interaction of lansoprazole and astemizole with tau polymers: potential new clinical use in diagnosis of Alzheimer's disease. 2010 1
38 20298971 Characterization of tau fibrillization in vitro. 2010 Mar 2
39 21433364 High Throughput Screening for Small Molecule Inhibitors of Heparin-induced Tau Fibril Formation 2010 1
40 19769346 Conformational changes specific for pseudophosphorylation at serine 262 selectively impair binding of tau to microtubules. 2009 Oct 27 1
41 18558718 A soluble oligomer of tau associated with fiber formation analyzed by NMR. 2008 Jul 15 3
42 18783251 The natively unfolded character of tau and its aggregation to Alzheimer-like paired helical filaments. 2008 Oct 7 1
43 17656819 Aluminum induces tau aggregation in vitro but not in vivo. 2007 Jul 2
44 16325769 Evidence for independent mechanisms and a multiple-hit model of tau assembly. 2006 Jan 20 1
45 16028903 High-resolution magic angle spinning NMR of the neuronal tau protein integrated in Alzheimer's-like paired helical fragments. 2005 Jul 27 1
46 15505366 Interaction of Alzheimer's disease amyloid beta peptide fragment 25-35 with tau protein, and with a tau peptide containing the microtubule binding domain. 2004 Oct 1
47 11437366 Role of cysteine-291 and cysteine-322 in the polymerization of human tau into Alzheimer-like filaments. 2001 Jul 6 7
48 10891598 Binding specificity of monoclonal antibody AD2: influence of the phosphorylation state of tau. 2000 May 31 1
49 10899436 Tau mutations in frontotemporal dementia FTDP-17 and their relevance for Alzheimer's disease. 2000 Jul 26 1
50 10075702 Heparin-induced conformational change in microtubule-associated protein Tau as detected by chemical cross-linking and phosphopeptide mapping. 1999 Mar 19 1