Title : In vitro 0N4R tau fibrils contain a monomorphic β-sheet core enclosed by dynamically heterogeneous fuzzy coat segments.

Pub. Date : 2019 Aug 13

PMID : 31358628






2 Functional Relationships(s)
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1 However, in vitro heparin-fibrillized 2N4R tau, which contains all four microtubule-binding repeats (4R), was recently found to adopt polymorphic structures. Heparin microtubule associated protein tau Homo sapiens
2 Here we use solid-state NMR spectroscopy to investigate the global fold and dynamics of heparin-fibrillized 0N4R tau. Heparin microtubule associated protein tau Homo sapiens