midostaurin

fms related receptor tyrosine kinase 3 ; Homo sapiens







150 Article(s)
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1 34653270 Use of midostaurin in mixed phenotype acute leukemia with FLT3 mutation: A case series. 2022 Feb 4
2 34774343 A review of FLT3 inhibitors in acute myeloid leukemia. 2022 Mar 1
3 34886738 Pharmacoeconomic considerations for acute myeloid leukemia pharmacotherapy. 2022 Feb 1
4 35198371 Gilteritinib monotherapy as a transplant bridging option for high risk FLT3-mutated AML with t(6;9)(p23;q34.1);DEK-NUP214 in morphological but not cytogenetic or molecular remission following standard induction chemotherapy. 2022 1
5 35462331 ABCB1 as a potential beneficial target of midostaurin in acute myeloid leukemia. 2022 Jun 4
6 35483923 FLT3 mutations in acute myeloid leukemia: a review focusing on clinically applicable drugs. 2022 Apr 30 1
7 35486475 Midostaurin plus intensive chemotherapy for younger and older Patients with AML and FLT3 internal tandem duplications. 2022 Apr 29 2
8 35496349 Therapeutic Management of Patients with FLT3 + Acute Myeloid Leukemia: Case Reports and Focus on Gilteritinib Monotherapy. 2022 3
9 35532877 FLT3-targeted treatment for acute myeloid leukemia. 2022 May 9 2
10 35549749 The FLT3 Y842D mutation may be highly sensitive to midostaurin: a case report. 2022 May 3
11 35565314 Target Therapy for Extramedullary Relapse of FLT3-ITD Acute Myeloid Leukemia: Emerging Data from the Field. 2022 Apr 27 1
12 35637252 Clinical outcomes in patients with relapsed/refractory FLT3-mutated acute myeloid leukemia treated with gilteritinib who received prior midostaurin or sorafenib. 2022 May 30 1
13 32949053 Midostaurin in combination with chemotherapy is most effective in patients with acute myeloid leukemia presenting with high FLT3-ITD allelic ratio who proceed to allogeneic stem cell transplantation while in first complete remission. 2021 Jan 2
14 33025066 Selective inhibition of aldo-keto reductase 1C3: a novel mechanism involved in midostaurin and daunorubicin synergism. 2021 Jan 4
15 33242449 Pharmacological impact of FLT3 mutations on receptor activity and responsiveness to tyrosine kinase inhibitors. 2021 Jan 1
16 33288862 Midostaurin after allogeneic stem cell transplant in patients with FLT3-internal tandem duplication-positive acute myeloid leukemia. 2021 May 2
17 33373830 Synergy of FLT3 inhibitors and the small molecule inhibitor of LIM kinase1/2 CEL_Amide in FLT3-ITD mutated Acute Myeloblastic Leukemia (AML) cells. 2021 Jan 1
18 33531064 Multiplexed single-cell mass cytometry reveals distinct inhibitory effects on intracellular phosphoproteins by midostaurin in combination with chemotherapy in AML cells. 2021 Feb 2 2
19 33598693 Clonal evolution of acute myeloid leukemia with FLT3-ITD mutation under treatment with midostaurin. 2021 Jun 3 3
20 33654204 Midostaurin reduces relapse in FLT3-mutant acute myeloid leukemia: the Alliance CALGB 10603/RATIFY trial. 2021 Sep 2
21 33677444 Choosing Antifungals for the Midostaurin-Treated Patient: Does CYP3A4 Outweigh Recommendations? A Brief Insight from Real Life. 2021 1
22 33879026 Post-transplantation maintenance with sorafenib or midostaurin for FLT3 positive AML patients - a multicenter retrospective observational study. 2021 Oct 1
23 34045454 FLT3 mutated acute myeloid leukemia: 2021 treatment algorithm. 2021 May 27 3
24 34172833 Actin cytoskeleton deregulation confers midostaurin resistance in FLT3-mutant acute myeloid leukemia. 2021 Jun 25 3
25 34424108 Safety of FLT3 inhibitors in patients with acute myeloid leukemia. 2021 Sep 1
26 34660293 Case Report: A Novel Activating FLT3 Mutation in Acute Myeloid Leukemia. 2021 1
27 34889359 What to use to treat AML: the role of emerging therapies. 2021 Dec 10 1
28 31291613 Necrotizing Hemorrhagic Gastritis following Acute Myeloid Leukemia Induction with Midostaurin: An Unexpected Complication. 2020 1
29 31471587 Hybridization capture-based next generation sequencing reliably detects FLT3 mutations and classifies FLT3-internal tandem duplication allelic ratio in acute myeloid leukemia: a comparative study to standard fragment analysis. 2020 Mar 1
30 31752581 Treatment practice and outcomes in FLT3-mutant acute myeloid leukemia in the pre-midostaurin era: a real-world experience from Australian tertiary hospitals. 2020 Apr 5
31 31782821 Midostaurin and cyclosporine drug interaction: A case report. 2020 Apr 1
32 31919472 FLT3 inhibitors in acute myeloid leukemia: ten frequently asked questions. 2020 Mar 1
33 31955389 Unique case of ANCA-negative pauci-immune necrotizing glomerulonephritis with diffuse alveolar hemorrhage, potentially associated with midostaurin. 2020 May 1
34 31967735 Effects of the multi-kinase inhibitor midostaurin in combination with chemotherapy in models of acute myeloid leukaemia. 2020 Mar 5
35 31970530 Cost-effectiveness of midostaurin in the treatment of newly diagnosed FLT3-mutated acute myeloid leukemia in France. 2020 Jun 4
36 32085993 A Phase II Study of Midostaurin and 5-Azacitidine for Untreated Elderly and Unfit Patients With FLT3 Wild-type Acute Myelogenous Leukemia. 2020 Apr 4
37 32109580 The role of small molecule Flt3 receptor protein-tyrosine kinase inhibitors in the treatment of Flt3-positive acute myelogenous leukemias. 2020 May 1
38 32215183 Quizartinib, a selective FLT3 inhibitor, maintains antileukemic activity in preclinical models of RAS-mediated midostaurin-resistant acute myeloid leukemia cells. 2020 Mar 17 1
39 32297538 Acute myeloid leukemia transformed to a targetable disease. 2020 May 1
40 32418523 FLT3 Inhibition in Acute Myeloid Leukaemia - Current Knowledge and Future Prospects. 2020 1
41 32468606 Anticancer activity of bisindole alkaloids derived from natural sources and synthetic bisindole hybrids. 2020 Sep 1
42 32477567 Advances in targeted therapy for acute myeloid leukemia. 2020 1
43 32514626 Antifungal prophylaxis and novel drugs in acute myeloid leukemia: the midostaurin and posaconazole dilemma. 2020 Jul 1
44 32545904 Cotargeting of XPO1 Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Acute Myeloid Leukemia. 2020 Jun 14 2
45 32567045 Combination treatment with CPX-351 and midostaurin in patients with secondary acute myeloid leukaemia that are FLT3 mutated: three cases and review of literature. 2020 Aug 1
46 32722298 Mechanisms Underlying Resistance to FLT3 Inhibitors in Acute Myeloid Leukemia. 2020 Jul 24 4
47 32754299 Genomic markers of midostaurin drug sensitivity in FLT3 mutated and FLT3 wild-type acute myeloid leukemia patients. 2020 Jul 21 5
48 32812818 Updated safety of midostaurin plus chemotherapy in newly diagnosed FLT3 mutation-positive acute myeloid leukemia: the RADIUS-X expanded access program. 2020 Dec 2
49 32825035 The FMS like Tyrosine Kinase 3 (FLT3) Is Overexpressed in a Subgroup of Multiple Myeloma Patients with Inferior Prognosis. 2020 Aug 19 1
50 32862867 FLT3 Inhibition in Acute Myeloid Leukemia. 2020 Sep 2