Pub. Date : 2022 May
PMID : 35549749
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The FLT3 Y842D mutation may be highly sensitive to midostaurin: a case report. | midostaurin | fms related receptor tyrosine kinase 3 | Homo sapiens |
| 2 | Following induction failure with standard dose idarubicin and cytarabine (IA), the patient received re-induction combined with midostaurin, a promising agent targeting mutant-FLT3, and IA regimen. | midostaurin | fms related receptor tyrosine kinase 3 | Homo sapiens |
| 3 | The present case revealed that Y842D, an uncommon activating mutation in the activation loop of FLT3, may be a midostaurin-sensitive mutation type in patients with acute myeloid leukaemia. | midostaurin | fms related receptor tyrosine kinase 3 | Homo sapiens |