Polysaccharides

CD4 molecule ; Homo sapiens







65 Article(s)
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1 35108536 Host glycocalyx captures HIV proximal to the cell surface via oligomannose-GlcNAc glycan-glycan interactions to support viral entry. 2022 Feb 1 2
2 33177194 Systematic Assessment of Antiviral Potency, Breadth, and Synergy of Triple Broadly Neutralizing Antibody Combinations against Simian-Human Immunodeficiency Viruses. 2021 Jan 13 1
3 34659153 The Role of L-Selectin in HIV Infection. 2021 1
4 34731616 Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies. 2021 Nov 2 1
5 32179120 Extraction of polysaccharides from maca: Characterization and immunoregulatory effects on CD4+ T cells. 2020 Jul 1 1
6 32760719 Targeting of the C-Type Lectin Receptor Langerin Using Bifunctional Mannosylated Antigens. 2020 1
7 33205023 Glycan Positioning Impacts HIV-1 Env Glycan-Shield Density, Function, and Recognition by Antibodies. 2020 Nov 20 1
8 30328700 Mapping of Neutralizing Antibody Epitopes on the Envelope of Viruses Obtained from Plasma Samples Exhibiting Broad Cross-Clade Neutralization Potential Against HIV-1. 2019 Feb 1
9 30729651 A novel anti-HIV-1 bispecific bNAb-lectin fusion protein engineered in a plant-based transient expression system. 2019 Aug 1
10 31466401 Glycan-Modified Apoptotic Melanoma-Derived Extracellular Vesicles as Antigen Source for Anti-Tumor Vaccination 2019 Aug 28 1
11 31564450 Antigenicity and immunogenicity of HIV-1 gp140 with different combinations of glycan mutation and V1/V2 region or V3 crown deletion. 2019 Dec 3 2
12 31678713 Chemically engineered glycan-modified cancer vaccines to mobilize skin dendritic cells. 2019 Dec 1
13 29633346 Frontline Science: Plasma and immunoglobulin G galactosylation associate with HIV persistence during antiretroviral therapy. 2018 Sep 1
14 29963041 Toll-Like Receptor 4 Triggering Promotes Cytosolic Routing of DC-SIGN-Targeted Antigens for Presentation on MHC Class I. 2018 1
15 30076101 Glycan Masking Focuses Immune Responses to the HIV-1 CD4-Binding Site and Enhances Elicitation of VRC01-Class Precursor Antibodies. 2018 Aug 21 2
16 30395637 HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies. 2018 Nov 1
17 27846415 Chinks in the armor of the HIV-1 Envelope glycan shield: Implications for immune escape from anti-glycan broadly neutralizing antibodies. 2017 Jan 15 1
18 28279830 Effects of partially dismantling the CD4 binding site glycan fence of HIV-1 Envelope glycoprotein trimers on neutralizing antibody induction. 2017 May 2
19 28287405 T cells control the generation of nanomolar-affinity anti-glycan antibodies. 2017 Apr 3 1
20 28445724 Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation. 2017 Apr 25 3
21 28632942 The glycan-mediated mechanism on the interactions of gp120 with CD4 and antibody: Insights from molecular dynamics simulation. 2017 Dec 18
22 28890362 Microsecond Dynamics and Network Analysis of the HIV-1 SOSIP Env Trimer Reveal Collective Behavior and Conserved Microdomains of the Glycan Shield. 2017 Oct 3 1
23 27489265 Changes in Structure and Antigenicity of HIV-1 Env Trimers Resulting from Removal of a Conserved CD4 Binding Site-Proximal Glycan. 2016 Oct 15 4
24 27581986 Structure of an N276-Dependent HIV-1 Neutralizing Antibody Targeting a Rare V5 Glycan Hole Adjacent to the CD4 Binding Site. 2016 Nov 15 6
25 26516768 A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo. 2015 Oct 2
26 25253346 Hyperglycosylated stable core immunogens designed to present the CD4 binding site are preferentially recognized by broadly neutralizing antibodies. 2014 Dec 2
27 25263953 Low antigen-specific CD4 T-cell immune responses despite normal absolute CD4 counts after long-term antiretroviral therapy an African cohort. 2014 Dec 1
28 23158834 Glycan-based DC-SIGN targeting vaccines to enhance antigen cross-presentation. 2013 Sep 1
29 23525136 Glycan-based DC-SIGN targeting to enhance antigen cross-presentation in anticancer vaccines. 2013 Feb 1 1
30 23658524 Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. 2013 1
31 23874792 The N276 glycosylation site is required for HIV-1 neutralization by the CD4 binding site specific HJ16 monoclonal antibody. 2013 1
32 24174970 O-glycosylation of NnTreg lymphocytes recognized by the Amaranthus leucocarpus lectin. 2013 1
33 24204277 Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes. 2013 Oct 1
34 22366522 Glycan-modified liposomes boost CD4+ and CD8+ T-cell responses by targeting DC-SIGN on dendritic cells. 2012 May 30 1
35 22490576 Inhibiting effect of Astragalus polysaccharides on the functions of CD4+CD25 highTreg cells in the tumor microenvironment of human hepatocellular carcinoma. 2012 Mar 1
36 23088960 Sialic acid cyclization of human Th homing receptor glycan associated with recurrent exacerbations of atopic dermatitis. 2012 Dec 1
37 20473945 Tumour-associated glycan modifications of antigen enhance MGL2 dependent uptake and MHC class I restricted CD8 T cell responses. 2011 Mar 15 2
38 21697467 Binding of the mannose-specific lectin, griffithsin, to HIV-1 gp120 exposes the CD4-binding site. 2011 Sep 2
39 20610714 HIV-1 gp120 determinants proximal to the CD4 binding site shift protective glycans that are targeted by monoclonal antibody 2G12. 2010 Sep 1
40 20616231 Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01. 2010 Aug 13 3
41 18237398 The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion. 2008 Jan 31 2
42 18322210 Identification of an N-linked glycosylation in the C4 region of HIV-1 envelope gp120 that is critical for recognition of neighboring CD4 T cell epitopes. 2008 Mar 15 1
43 18385254 Natural resistance of human immunodeficiency virus type 1 to the CD4bs antibody b12 conferred by a glycan and an arginine residue close to the CD4 binding loop. 2008 Jun 1
44 17301214 A human monoclonal immunoglobulin M reduces bacteremia and inflammation in a mouse model of systemic pneumococcal infection. 2007 Apr 1
45 17947541 Inhibitory role of CXCR4 glycan in CD4-independent X4-tropic human immunodeficiency virus type 1 infection and its abrogation in CD4-dependent infection. 2007 Nov 5
46 16711753 A combination of molecular dynamics and docking calculations to explore the binding mode of ADS-J1, a polyanionic compound endowed with anti-HIV-1 activity. 2006 May-Jun 1
47 16918445 Immunology of O-glycosylated proteins: approaches to the design of a MUC1 glycopeptide-based tumor vaccine. 2006 Aug 1
48 16160185 Identification of two N-linked glycosylation sites within the core of the simian immunodeficiency virus glycoprotein whose removal enhances sensitivity to soluble CD4. 2005 Oct 2
49 16275921 Modulation of surgical fibrosis by microbial zwitterionic polysaccharides. 2005 Nov 15 1
50 15163414 Polysaccharide processing and presentation by the MHCII pathway. 2004 May 28 1