114 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
51 | 22801429 | Structural features and domain organization of huntingtin fibrils. | 2012 Sep 14 | 1 |
52 | 22905336 | Corticostriatal dysfunction and glutamate transporter 1 (GLT1) in Huntington's disease: interactions between neurons and astrocytes. | 2012 Jul 1 | 2 |
53 | 22978784 | All-atom stability and oligomerization simulations of polyglutamine nanotubes with and without the 17-amino-acid N-terminal fragment of the Huntingtin protein. | 2012 Oct 11 | 1 |
54 | 23225006 | Fibrillogenesis of huntingtin and other glutamine containing proteins. | 2012 | 2 |
55 | 23236391 | Analysis of proteolytic processes and enzymatic activities in the generation of huntingtin n-terminal fragments in an HEK293 cell model. | 2012 | 2 |
56 | 23394029 | [Is Huntington's disease a neurological or psychiatric disorder? case report]. | 2012 Sep-Oct | 1 |
57 | 23560303 | Single amino acid and trinucleotide repeats: function and evolution. | 2012 | 1 |
58 | 21278081 | Functional and systems biology approaches to Huntington's disease. | 2011 May | 2 |
59 | 21882412 | Huntington’s Disease Pathogenesis: Mechanisms and Pathways | 2011 | 2 |
60 | 21896647 | Changes in BiP availability reveal hypersensitivity to acute endoplasmic reticulum stress in cells expressing mutant huntingtin. | 2011 Oct 1 | 2 |
61 | 21909428 | Targeting several CAG expansion diseases by a single antisense oligonucleotide. | 2011 | 2 |
62 | 19338577 | Neuroprotective effects of calmodulin peptide 76-121aa: disruption of calmodulin binding to mutant huntingtin. | 2010 Jan | 1 |
63 | 20219972 | Analyzing the birth and propagation of two distinct prions, [PSI+] and [Het-s](y), in yeast. | 2010 May 1 | 1 |
64 | 20552561 | Synthesis of pathological and nonpathological human exon 1 huntingtin. | 2010 Jul | 2 |
65 | 20873112 | [The role of mitochondria in the pathogenesis of Huntington's disease]. | 2010 | 1 |
66 | 21095569 | Identification and evaluation of small molecule pan-caspase inhibitors in Huntington's disease models. | 2010 Nov 24 | 3 |
67 | 19270310 | Regulator of calcineurin (RCAN1-1L) is deficient in Huntington disease and protective against mutant huntingtin toxicity in vitro. | 2009 May 1 | 1 |
68 | 19429504 | Small molecule drug discovery for Huntington's Disease. | 2009 May | 1 |
69 | 19549822 | Single homopolypeptide chains collapse into mechanically rigid conformations. | 2009 Aug 4 | 1 |
70 | 19664996 | Single-step detection of mutant huntingtin in animal and human tissues: a bioassay for Huntington's disease. | 2009 Dec 1 | 1 |
71 | 19710014 | Phosphorylation of threonine 3: implications for Huntingtin aggregation and neurotoxicity. | 2009 Oct 23 | 1 |
72 | 20640815 | Mutation effects on structural stability of polyglutamine peptides by molecular dynamics simulation. | 2009 Mar | 1 |
73 | 18243803 | Molecular dynamics simulation study on the structural stabilities of polyglutamine peptides. | 2008 Apr | 1 |
74 | 18279698 | Excitotoxic neuronal death and the pathogenesis of Huntington's disease. | 2008 Apr | 2 |
75 | 18386172 | Investigation of tRNA(Leu/Lys) and ATPase 6 genes mutations in Huntington's disease. | 2008 Nov | 1 |
76 | 18488016 | Towards a transgenic model of Huntington's disease in a non-human primate. | 2008 Jun 12 | 2 |
77 | 19118173 | Cytoplasmic inclusions of Htt exon1 containing an expanded polyglutamine tract suppress execution of apoptosis in sympathetic neurons. | 2008 Dec 31 | 1 |
78 | 17409200 | Triplet repeat mutation length gains correlate with cell-type specific vulnerability in Huntington disease brain. | 2007 May 15 | 1 |
79 | 17413322 | Characterization of huntingtin pathologic fragments in human Huntington disease, transgenic mice, and cell models. | 2007 Apr | 2 |
80 | 18077673 | Mitochondrial sensitivity and altered calcium handling underlie enhanced NMDA-induced apoptosis in YAC128 model of Huntington's disease. | 2007 Dec 12 | 1 |
81 | 16524881 | Extended polyglutamine tracts cause aggregation and structural perturbation of an adjacent beta barrel protein. | 2006 May 5 | 1 |
82 | 20396523 | Therapeutic Strategies in Huntington's Disease. | 2006 Dec | 1 |
83 | 15720212 | Huntington's disease: new frontiers for molecular and cell therapy. | 2005 Feb | 1 |
84 | 15824100 | Modulation of prion-dependent polyglutamine aggregation and toxicity by chaperone proteins in the yeast model. | 2005 Jun 17 | 1 |
85 | 16040812 | Formation of morphologically similar globular aggregates from diverse aggregation-prone proteins in mammalian cells. | 2005 Aug 2 | 1 |
86 | 16043692 | Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease. | 2005 Aug 2 | 1 |
87 | 15140195 | Modulating huntingtin half-life alters polyglutamine-dependent aggregate formation and cell toxicity. | 2004 May | 1 |
88 | 12888569 | Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington's disease. | 2003 Oct 17 | 1 |
89 | 14570710 | Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis. | 2003 Dec 15 | 1 |
90 | 11870213 | Perinuclear localization of huntingtin as a consequence of its binding to microtubules through an interaction with beta-tubulin: relevance to Huntington's disease. | 2002 Mar 1 | 1 |
91 | 12235581 | [Molecular basis of Huntington's disease and possible pathogenic mechanisms]. | 2002 Aug 1-15 | 1 |
92 | 12486229 | Glutamine/proline-rich PQE-1 proteins protect Caenorhabditis elegans neurons from huntingtin polyglutamine neurotoxicity. | 2002 Dec 24 | 1 |
93 | 12499864 | Transient osmotic stress facilitates mutant huntingtin aggregation. | 2002 Dec 20 | 1 |
94 | 12518531 | [The DNA test in the diagnosis of Huntington disease]. | 2002 | 1 |
95 | 11359930 | Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation. | 2001 May | 2 |
96 | 11461154 | Identification of the full-length huntingtin- interacting protein p231HBP/HYPB as a DNA-binding factor. | 2001 Jul | 1 |
97 | 11719265 | Expression of the Huntington's disease transgene in neural stem cell cultures from R6/2 transgenic mice. | 2001 Oct-Nov 1 | 1 |
98 | 11723754 | [From gene to disease; HD gene and Huntington disease]. | 2001 Nov 3 | 1 |
99 | 10958656 | Huntingtin's WW domain partners in Huntington's disease post-mortem brain fulfill genetic criteria for direct involvement in Huntington's disease pathogenesis. | 2000 Sep 1 | 2 |
100 | 10961047 | [Huntington disease. A review]. | 2000 Jun | 2 |