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34445734 | Decreased Interactions between Calmodulin and a Mutant Huntingtin Model Might Reduce the Cytotoxic Level of Intracellular Ca2+: A Molecular Dynamics Study. | 2021 Aug 21 |
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32266815 | Evidence of the Reduced Abundance of Proline cis Conformation in Protein Poly Proline Tracts. | 2020 Apr 29 |
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| 3 |
32402249 | Flanking Regions Determine the Structure of the Poly-Glutamine in Huntingtin through Mechanisms Common among Glutamine-Rich Human Proteins. | 2020 Jul 7 |
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| 4 |
33096080 | Structural Model of the Proline-Rich Domain of Huntingtin Exon-1 Fibrils. | 2020 Nov 17 |
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| 5 |
30538129 | High-mobility group box 1 links sensing of reactive oxygen species by huntingtin to its nuclear entry. | 2019 Feb 8 |
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30808748 | Probing initial transient oligomerization events facilitating Huntingtin fibril nucleation at atomic resolution by relaxation-based NMR. | 2019 Feb 26 |
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29358329 | Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers. | 2018 Mar 9 |
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29754822 | A Liquid to Solid Phase Transition Underlying Pathological Huntingtin Exon1 Aggregation. | 2018 May 17 |
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| 9 |
30252478 | Dynamics of the Proline-Rich C-Terminus of Huntingtin Exon-1 Fibrils. | 2018 Oct 18 |
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| 10 |
27458341 | Altered Co-Translational Processing Plays a Role in Huntington's Pathogenesis-A Hypothesis. | 2016 |
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| 11 |
27595037 | An Intrabody Drug (rAAV6-INT41) Reduces the Binding of N-Terminal Huntingtin Fragment(s) to DNA to Basal Levels in PC12 Cells and Delays Cognitive Loss in the R6/2 Animal Model. | 2016 |
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| 12 |
24412394 | Autoinhibitory structure of the WW domain of HYPB/SETD2 regulates its interaction with the proline-rich region of huntingtin. | 2014 Mar 4 |
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| 13 |
22178478 | Inhibiting the nucleation of amyloid structure in a huntingtin fragment by targeting α-helix-rich oligomeric intermediates. | 2012 Feb 3 |
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| 14 |
23012356 | Identification of a karyopherin β1/β2 proline-tyrosine nuclear localization signal in huntingtin protein. | 2012 Nov 16 |
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| 15 |
21332223 | Natural osmolytes remodel the aggregation pathway of mutant huntingtin exon 1. | 2011 Mar 29 |
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| 16 |
21566141 | Interaction with polyglutamine-expanded huntingtin alters cellular distribution and RNA processing of huntingtin yeast two-hybrid protein A (HYPA). | 2011 Jul 15 |
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| 17 |
19710014 | Phosphorylation of threonine 3: implications for Huntingtin aggregation and neurotoxicity. | 2009 Oct 23 |
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| 18 |
18094623 | HspB8 and Bag3: a new chaperone complex targeting misfolded proteins to macroautophagy. | 2008 Feb |
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| 19 |
18768695 | Intrabodies binding the proline-rich domains of mutant huntingtin increase its turnover and reduce neurotoxicity. | 2008 Sep 3 |
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| 20 |
17373643 | Mapping of the epitope of monoclonal antibody 2B4 to the proline-rich region of human Huntingtin, a region critical for aggregation and toxicity. | 2007 May |
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| 21 |
17161366 | Structural insights into the specific binding of huntingtin proline-rich region with the SH3 and WW domains. | 2006 Dec |
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| 22 |
14715959 | Huntingtin bodies sequester vesicle-associated proteins by a polyproline-dependent interaction. | 2004 Jan 7 |
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| 23 |
12486229 | Glutamine/proline-rich PQE-1 proteins protect Caenorhabditis elegans neurons from huntingtin polyglutamine neurotoxicity. | 2002 Dec 24 |
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| 24 |
9700202 | Huntingtin interacts with a family of WW domain proteins. | 1998 Sep |
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| 25 |
9079622 | SH3 domain-dependent association of huntingtin with epidermal growth factor receptor signaling complexes. | 1997 Mar 28 |
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