ipragliflozin

solute carrier family 5 (sodium/glucose cotransporter), member 2 ; Mus musculus







30 Article(s)
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1 34494293 Withdrawn: SGLT2 inhibitor ipragliflozin poses a low risk of hypoglycaemia owing to its blood glucose-dependent urinary glucose excretion mechanism in mice. 2022 Jun 2
2 35192632 Ipragliflozin attenuates non-alcoholic steatohepatitis development in an animal model. 2022 2
3 33611885 Ipragliflozin, an SGLT2 Inhibitor, Ameliorates High-Fat Diet-Induced Metabolic Changes by Upregulating Energy Expenditure through Activation of the AMPK/ SIRT1 Pathway. 2021 Nov 3
4 34298949 Ipragliflozin Ameliorates Diabetic Nephropathy Associated with Perirenal Adipose Expansion in Mice. 2021 Jul 8 2
5 34487707 SGLT2 inhibitor ipragliflozin exerts antihyperglycemic effects via the blood glucose-dependent increase in urinary glucose excretion in type 2 diabetic mice. 2021 Nov 5 3
6 31955626 Therapeutic Effects of SGLT2 Inhibitor Ipragliflozin and Metformin on NASH in Type 2 Diabetic Mice. 2020 Feb - May 5
7 32821334 Ipragliflozin-induced improvement of liver steatosis in obese mice may involve sirtuin signaling. 2020 Jul 27 1
8 33015603 Low dose of sodium-glucose transporter 2 inhibitor ipragliflozin attenuated renal dysfunction and interstitial fibrosis in adenine-induced chronic kidney disease in mice without diabetes. 2020 Sep 1
9 30914436 Inhibition of Sodium Glucose Cotransporter 2 Attenuates the Dysregulation of Kelch-Like 3 and NaCl Cotransporter in Obese Diabetic Mice. 2019 May 2
10 31234839 Ipragliflozin-induced adipose expansion inhibits cuff-induced vascular remodeling in mice. 2019 Jun 24 1
11 31782258 SGLT2 inhibitor ipragliflozin alone and combined with pioglitazone prevents progression of nonalcoholic steatohepatitis in a type 2 diabetes rodent model. 2019 Nov 2
12 31888083 Ipragliflozin Ameliorates Endoplasmic Reticulum Stress and Apoptosis through Preventing Ectopic Lipid Deposition in Renal Tubules. 2019 Dec 26 1
13 29154936 Antidiabetic and antiobesity effects of SGLT2 inhibitor ipragliflozin in type 2 diabetic mice fed sugar solution. 2018 Jan 5 3
14 29352520 Ipragliflozin improves mitochondrial abnormalities in renal tubules induced by a high-fat diet. 2018 Sep 1
15 29374293 Effects of the SGLT2 inhibitor ipragliflozin on various diabetic symptoms and progression of overt nephropathy in type 2 diabetic mice. 2018 Apr 2
16 29425766 Antidiabetic effects of SGLT2 inhibitor ipragliflozin in type 2 diabetic mice fed diets containing different carbohydrate contents. 2018 Mar 15 2
17 29507299 Comprehensive renoprotective effects of ipragliflozin on early diabetic nephropathy in mice. 2018 Mar 5 1
18 29702076 Prevention of progression of diabetic nephropathy by the SGLT2 inhibitor ipragliflozin in uninephrectomized type 2 diabetic mice. 2018 Jul 5 2
19 30021338 Effects of the SGLT2 inhibitor ipragliflozin on food intake, appetite-regulating hormones, and arteriovenous differences in postprandial glucose levels in type 2 diabetic rats. 2018 Sep 1
20 28506912 Characterization and comparison of SGLT2 inhibitors: Part 3. Effects on diabetic complications in type 2 diabetic mice. 2017 Aug 15 1
21 26450351 Effects of the combination of SGLT2 selective inhibitor ipragliflozin and various antidiabetic drugs in type 2 diabetic mice. 2016 Feb 2
22 26731267 The Selective SGLT2 Inhibitor Ipragliflozin Has a Therapeutic Effect on Nonalcoholic Steatohepatitis in Mice. 2016 1
23 26977813 Ipragliflozin Improves Hepatic Steatosis in Obese Mice and Liver Dysfunction in Type 2 Diabetic Patients Irrespective of Body Weight Reduction. 2016 1
24 27327650 Sodium-Glucose Cotransporter 2 Inhibitor and a Low Carbohydrate Diet Affect Gluconeogenesis and Glycogen Content Differently in the Kidney and the Liver of Non-Diabetic Mice. 2016 1
25 27833913 Glycemic Control with Ipragliflozin, a Novel Selective SGLT2 Inhibitor, Ameliorated Endothelial Dysfunction in Streptozotocin-Induced Diabetic Mouse. 2016 3
26 26366172 Effect of Repetitive Glucose Spike and Hypoglycaemia on Atherosclerosis and Death Rate in Apo E-Deficient Mice. 2015 1
27 23707905 Effects of SGLT2 selective inhibitor ipragliflozin on hyperglycemia, hyperlipidemia, hepatic steatosis, oxidative stress, inflammation, and obesity in type 2 diabetic mice. 2013 Sep 5 3
28 22139434 Pharmacological profile of ipragliflozin (ASP1941), a novel selective SGLT2 inhibitor, in vitro and in vivo. 2012 Apr 5
29 22507206 Discovery of Ipragliflozin (ASP1941): a novel C-glucoside with benzothiophene structure as a potent and selective sodium glucose co-transporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes mellitus. 2012 May 15 2
30 22971845 Antidiabetic effects of SGLT2-selective inhibitor ipragliflozin in streptozotocin-nicotinamide-induced mildly diabetic mice. 2012 3