Title : Characterization and comparison of SGLT2 inhibitors: Part 3. Effects on diabetic complications in type 2 diabetic mice.

Pub. Date : 2017 Aug 15

PMID : 28506912






1 Functional Relationships(s)
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1 While all SGLT2 inhibitors exerted comparable effects in reducing hyperglycemia, improvement of these diabetes-related diseases and complications was more potent with the two long-acting drugs (ipragliflozin and dapagliflozin) than with the four intermediate-acting four drugs (tofogliflozin, canagliflozin, empagliflozin, and luseogliflozin), albeit without statistical significance. ipragliflozin solute carrier family 5 (sodium/glucose cotransporter), member 2 Mus musculus