Title : Rucaparib: A Poly(ADP-Ribose) Polymerase Inhibitor for BRCA-Mutated Relapsed Ovarian Cancer.

Pub. Date : 2019 Apr

PMID : 29166829






2 Functional Relationships(s)
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1 In patients with deleterious BRCA1/2 mutation, an overall response rate of 80% was achieved in the phase II trial Assessment of Rucaparib in Ovarian CancEr Trial 2 (ARIEL2). rucaparib BRCA1 DNA repair associated Homo sapiens
2 CONCLUSION: Rucaparib appears to be a safe and effective new option in the treatment of relapsed, advanced BRCA1/2 mutant ovarian cancer. rucaparib BRCA1 DNA repair associated Homo sapiens