Mitomycin

BRCA1 DNA repair associated ; Homo sapiens







20 Article(s)
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1 32843487 Biallelic variants in BRCA1 gene cause a recognisable phenotype within chromosomal instability syndromes reframed as BRCA1 deficiency. 2021 Sep 1
2 33536037 Neoadjuvant therapy of BRCA1-driven ovarian cancer by combination of cisplatin, mitomycin C and doxorubicin. 2021 Feb 3 1
3 34454564 Cytotoxic and targeted therapy for BRCA1/2-driven cancers. 2021 Aug 28 2
4 32591974 Mitomycin C plus cisplatin for systemic treatment of recurrent BRCA1-associated ovarian cancer. 2020 Dec 2
5 30247247 Efficacy of Neoadjuvant Therapy With Cisplatin Plus Mitomycin C in BRCA1-Mutated Ovarian Cancer. 2018 Oct 2
6 27555886 Cytotoxic and targeted therapy for hereditary cancers. 2016 2
7 30452211 [Specific features of drug sensitivity of hereditary cancers]. 2016 1
8 25652403 Functional variant analyses (FVAs) predict pathogenicity in the BRCA1 DNA double-strand break repair pathway. 2015 Jun 1 1
9 24342616 HUWE1 interacts with BRCA1 and promotes its degradation in the ubiquitin-proteasome pathway. 2014 Feb 14 1
10 24472556 HUWE1 interacts with BRCA1 and promotes its degradation in the ubiquitin-proteasome pathway. 2014 Feb 21 1
11 25186150 Evidence for clinical efficacy of mitomycin C in heavily pretreated ovarian cancer patients carrying germ-line BRCA1 mutation. 2014 Oct 3
12 24124520 Ouabain, a cardiac glycoside, inhibits the Fanconi anemia/BRCA pathway activated by DNA interstrand cross-linking agents. 2013 2
13 20625817 Ionizing radiation or mitomycin-induced micronuclei in lymphocytes of BRCA1 or BRCA2 mutation carriers. 2011 Jun 3
14 20711688 A 67-year-old woman with BRCA 1 mutation associated with pancreatic adenocarcinoma. 2011 Sep 1
15 20174566 Use of DNA-damaging agents and RNA pooling to assess expression profiles associated with BRCA1 and BRCA2 mutation status in familial breast cancer patients. 2010 Feb 19 1
16 19584259 PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2. 2009 Jul 1
17 17671173 BRCA1- and BRCA2-deficient cells are sensitive to etoposide-induced DNA double-strand breaks via topoisomerase II. 2007 Aug 1 1
18 14751517 Primary fibroblasts from BRCA1 heterozygotes display an abnormal G1/S cell cycle checkpoint following UVA irradiation but show normal levels of micronuclei following oxidative stress or mitomycin C treatment. 2004 Feb 1 2
19 11406561 Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation. 2001 Jun 15 3
20 10884389 Repression of BRCA1 through a feedback loop involving p53. 2000 Oct 13 2