2-oxindole

cyclin dependent kinase 2 ; Homo sapiens







7 Article(s)
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1 35623140 Novel Azine Linked Hybrids of 2-Indolinone and Thiazolodinone Scaffolds as CDK2 Inhibitors with Potential Anticancer Activity: In Silico Design, Synthesis, Biological, Molecular Dynamics and Binding Free Energy Studies. 2022 Sep 1
2 33327806 Novel oxindole/benzofuran hybrids as potential dual CDK2/GSK-3β inhibitors targeting breast cancer: design, synthesis, biological evaluation, and in silico studies. 2021 Dec 4
3 18307332 Fragment-based de novo ligand design by multiobjective evolutionary optimization. 2008 Mar 2
4 17266627 3D-QSAR CoMFA study on oxindole derivatives as cyclin dependent kinase 1 (CDK1) and cyclin dependent kinase 2 (CDK2) inhibitors. 2007 Jan 4
5 15012993 A new series of potent oxindole inhibitors of CDK2. 2004 Feb 23 2
6 12659774 Synthesis of potent oxindole CDK2 inhibitors. 2003 Apr 17 2
7 11728181 Oxindole-based inhibitors of cyclin-dependent kinase 2 (CDK2): design, synthesis, enzymatic activities, and X-ray crystallographic analysis. 2001 Dec 6 4