Title : Fragment-based de novo ligand design by multiobjective evolutionary optimization.

Pub. Date : 2008 Mar

PMID : 18307332






2 Functional Relationships(s)
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Protein Name
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1 The performance of GANDI is tested on cyclin-dependent kinase 2 (CDK2) using a library of about 14 000 fragments and the binding mode of a known oxindole inhibitor to bias the design. 2-oxindole cyclin dependent kinase 2 Homo sapiens
2 The performance of GANDI is tested on cyclin-dependent kinase 2 (CDK2) using a library of about 14 000 fragments and the binding mode of a known oxindole inhibitor to bias the design. 2-oxindole cyclin dependent kinase 2 Homo sapiens