Adenine

cyclin dependent kinase 2 ; Homo sapiens







9 Article(s)
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Pub. Year
#Total Relationships
1 32210718 Adenine inhibits growth of hepatocellular carcinoma cells via AMPK-mediated S phase arrest and apoptotic cascade. 2020 1
2 28827110 Synthesis and biological evaluation of N9-cis-cyclobutylpurine derivatives for use as cyclin-dependent kinase (CDK) inhibitors. 2017 Sep 15 2
3 23864105 An in silico exploration of the interaction mechanism of pyrazolo[1,5-a]pyrimidine type CDK2 inhibitors. 2013 Sep 1
4 22927831 Chemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cells. 2012 Aug 2
5 11170642 Crystal structure of human cyclin-dependent kinase 2 in complex with the adenine-derived inhibitor H717. 2001 Feb 15 1
6 11377199 Inhibitor binding to active and inactive CDK2: the crystal structure of CDK2-cyclin A/indirubin-5-sulphonate. 2001 May 9 1
7 9030780 Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine. 1997 Jan 15 1
8 8610110 Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase. 1996 Apr 2 1
9 7479711 Multiple modes of ligand recognition: crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine. 1995 Aug 3