Title : Adenine inhibits growth of hepatocellular carcinoma cells via AMPK-mediated S phase arrest and apoptotic cascade.

Pub. Date : 2020

PMID : 32210718






1 Functional Relationships(s)
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1 Western blot analysis showed that adenine reduced expression of cyclin A/D1 and cyclin-dependent kinase (CDK)2 and upregulated p53, p21, Bax, PUMA, and NOXA in HepG2 cell. Adenine cyclin dependent kinase 2 Homo sapiens